ENHANCEMENT OF PHYSICAL BIOCHEMISTRY IN OKLAHOMA

该IDEA计划的目标是加强和提高物理 生物化学和结构生物学研究工作在五个主要 参与机构在俄克拉荷马州。这一长期目标将是 通过（一）教师发展（二）教师启动支持，以及 (iii)发展必要的基础设施， 先进的结构生物学研究， 生物化学在全国各地关键项目的采购 设备将允许招聘新的教师在结构 生物学，并将刺激特定研究人员的研究计划 在整个国家。该计划还将有利于广泛的努力， 通过增加合作，每个机构现有教师的数量 机会和互动。 教师发展的目标是在 目前的方案，促进征聘/搬迁两名 建立了NIH资助的研究人员，他们是结构科学家， 和两个最近招募的初级教师，谁将得到新的援助， 设备和资源需要为他们的发展研究计划。的 该计划将提供启动支持，以促进新的招聘 初级和高级教师在结构生物学的广泛领域，在 特别是直接从事核磁共振光谱学和蛋白质研究的研究人员 结晶学 这一战略的一个重要组成部分将是 购买X射线晶体学设备。本IDEA的影响 该方案将对个别机构和国家的几倍。 (1)四个教师的研究计划将通过具体的加强 01年的设备和支持。(2)一个大型的研究项目 一组既定的教师将受益于购买设备 旨在加强他们在物理生物化学方面的研究工作。（三） 招聘新的结构生物学教师将是可能的，由于 关键设备的购置。(4)该计划将产生广泛的影响 通过使俄克拉荷马州在高质量的表演能力方面更具竞争力， 生物医学研究

The goal of this IDeA Program is to strengthen and increase Physical Biochemistry and Structural Biology research efforts at the five major participating institutions in Oklahoma. This long-range goal will be accomplished by (i) faculty development (ii) faculty start-up support, and (iii) developing the infrastructure necessary to conduct broad-based state-of-the-art Structural Biology research by upgrading equipment for Physical Biochemistry throughout the State. The acquisition of key items of equipment will allow the recruitment of new faculty in Structural Biology and will stimulate the research programs of specific investigators throughout the State. The Program will also benefit the efforts of a wide number of present faculty at each institution by increasing collaborative opportunities and interactions. Faculty development is targeted in the present program by facilitating the recruitment/relocation of two established NIH funded investigators, who are structural-based scientists, and two recently recruited junior faculty, who will be aided by new equipment and resources needed for their developing research programs. The Program will provide start-up support to facilitate recruitment of new junior and senior faculty in the broad area of Structural Biology, in particular investigators working directly in NMR spectroscopy and protein crystallography. A substantial component of this strategy will be the purchase of X-ray crystallography equipment. The impact of this IDeA Program will be several-fold on the individual institutions and State. (1) The research programs of four faculty will be enhanced by specific equipment and support in year 01. (2) The research programs of a large group of established faculty will benefit by the acquisition of equipment targeted to enhance their research efforts in Physical Biochemistry. (3) The recruitment of new Structural Biology faculty will be possible due to the acquisition of key equipment. (4) The Program will have a broad impact by making Oklahoma more competitive in the ability to perform high quality biomedical research.