Does childhood physical activity, fitness and fatness impact on knee structural change 20 years later?

增加儿童期体力活动(PA)的参与和减少儿童肥胖的干预措施被认为是为了减少成年后心血管和其他疾病的风险，但儿童期PA和肥胖症与成年后膝骨性关节炎变化的相关性尚不清楚。这项研究对一大批澳大利亚儿童进行了20多年的跟踪调查，将首次使用强大的磁共振成像技术来确定这些联系。

Interventions to increase participation of physical activity (PA) and to reduce obesity in childhood are advocated to reduce the risks of cardiovascular and other diseases in adulthood, but the associations of childhood PA and obesity with knee osteoarthritic changes in adulthood are unknown. This study, with follow-up of a large cohort of Australian children over 20 years, will be the first to determine these associations using the powerful technique of magnetic resonance imaging.