MODERATE ALCOHOL USE--THE HETEROGENEITY OF ABSTENTION

申请人摘要：拟议项目的目的是确定是否 戒酒者的身体和精神疾病的患病率比 以及，在戒酒者中，确定是否 在身体和精神疾病的患病率方面存在差异。 社会人口统计指标、生活方式和种族/文化差异将 对于戒酒者和轻中度饮酒者也要进行检查。至 为此，一个具有全国代表性的数据集，国家纵向 酒精流行病学调查将用于：(1)从以下方面衡量酒精使用 频次、数量和酗酒；(2)区分 基于健康、吸烟、种族和社会差异的戒酒 人口统计指标，(3)在弃权的人中确定是否有 不同类型戒酒者患心脏病风险的差异；从不生病 饮酒者，健康的从不饮酒者，曾经的清淡，适度，重度饮酒者， 滥用饮酒者，(4)在禁酒者中确定是否有 不同类型戒酒者患抑郁症风险的差异，(5)决定是否 戒酒的人比不戒酒的人有更高的抑郁/情绪问题 在控制社会人口变量、种族和 身体疾病，以及(6)确定戒酒者是否有更高的心脏水平 疾病，与那些不戒酒的人相比。 从这些活动中获得的信息将有两个相关目的：第一， 增进我们对弃权的相关性的了解，特别是 不同年龄、性别和种族的差异。二、增强能力 将戒酒者归入具有病因学意义的相关类别 适量饮酒与健康。通常是适度饮酒的人，他们也可能是 在许多不同的生活方式和健康状况衡量标准中， 通常与弃权者相比，后者可能具有以下措施的组合 明显不那么温和，或者至少是非常不同。因此， 而不是基于酒精来衡量健康结果的差异 在适度和节食类别之间，研究人员经常 例如，将患病的酗酒者与相对健康的人进行比较 适量饮酒者。同样，生病的从不饮酒的人可能会被比作 中度饮酒者。在这两种情况下， 适度饮酒被其他可能影响饮酒的因素所掩盖 健康结果与适度饮酒或戒酒无关。 这个项目的结果将允许对角色进行更有洞察力的检查 适量饮酒可预防某些慢性病。

APPLICANT'S ABSTRACT: The purposes of the proposed project are to determine if abstainers have a higher prevalence of physical and mental illness compared to light-to-moderate alcohol drinkers and, amongst abstainers, determine if differences exist in regard to prevalence of physical and mental illness. Socio-demographic measures, lifestyle and ethnic/cultural differences will also be examined for abstainers and light-to-moderate alcohol consumers. To this end, a nationally representative data set, the National Longitudinal Alcohol Epidemiologic Survey will be used to: (1) measure alcohol use in terms of frequency quantity and binge drinking, (2) distinguish amongst those abstaining based on differences in health, smoking, ethnicity and socio- demographic measures, (3) determine amongst those abstaining if there are differences in risk of heart disease by type of abstainer; sick never drinkers, healthy never drinkers, former light, moderate, heavy drinkers, abusing drinkers, (4) determine amongst those abstaining if there are differences in risk of depression by type of abstainer, (5) determine if abstainers have higher levels of depression/mood problems than those not abstaining when controlling for socio-demographic variables, ethnicity and physical illness, and (6) determine if abstainers have higher levels of heart disease, compared to those not abstaining. Information from these activities will serve two related purposes: First, to increase our understanding of the correlates of abstention, particularly differences across age, gender and ethnicity. Second, to increase our ability to classify abstainers into etiologically meaningful categories relevant to moderate alcohol and health. Often moderate drinkers, who may also be moderate in many different measures of lifestyle and health status, are typically compared to abstainers who may have combinations of measures that are considerably less moderate, or at the least, very different. Thus, instead of measuring differences in health outcomes based on alcohol consumption between moderate and abstention categories, researchers frequently are comparing, for example, sick former heavy drinkers with relatively healthy moderate drinkers. Similarly, sick never drinkers might be compared to moderate alcohol drinkers. In either case, the possible beneficial effect of moderate alcohol use is obscured by other factors that may be influencing health outcomes independently from moderate alcohol use or abstention. Results from this project will allow a more insightful examination of the role of moderate alcohol in protecting against certain chronic diseases.