GENERAL CLINICAL RESEARCH CENTER

科学上的卓越和开放的合作传统 教员将促进在阿尔伯特大学建立一个新的GCRC项目 爱因斯坦医学院-蒙特菲奥里医学中心。爱因斯坦- Montefiore GCRC将为布朗克斯和韦斯特切斯特的居民提供服务 纽约州的县总数约为190万人，其中一半来自 少数民族、种族和民族群体。两人的坚定承诺 各机构为GCRC倡议提供了新的空间和便利 获取以患者为中心的研究资源。对世界经济发展的热情 来自中国的44名研究人员参与了GCRC计划 总共有2个科室--包括临床和基础科学--谁将是 参与本申请中描述的项目，实施 联邦政府资助的超过1400万美元的研究支持。这些调查员- 启动的项目涉及多种人类疾病，例如 糖尿病、肺结核、肝豆状核变性、肝病、镰状细胞 贫血，多囊肾病，系统性红斑狼疮， 感染性腹泻、肥胖、心血管疾病、阳萎、宫颈 癌症和痴呆症。这些项目汇集了跨学科的知识 主要由美国国立卫生研究院资助但缺乏足够资源的研究 用于临床研究。GCRC的设施位于一个校园内 在布朗克斯；GCRC行政、门诊、样本处理 实验室和生物统计学部分将设在学院 医学部与住院病人的每日入院和特别程序 在毗邻的大学医院的病房。大量的中心和 共享科学设施将为GCRC的调查人员提供支持。 爱因斯坦GCRC将提供一个环境来进行人体研究和 促进数据采集、管理和分析，并将 鼓励基础和临床科学家之间的合作。最后， GCRC将作为学会承诺的核心 培养年轻的内科科学家。该中心的管理 将包括医学和医院学院的行政人员， 该中心将由一群经验丰富的调查人员指导 具有GCRC以前的经验，基础科学知识和强大的 独立的科学项目。

A tradition of scientific excellence and open collaboration among the faculty will foster the establishment of a new GCRC program at the Albert Einstein College of Medicine-Montefiore Medical Center. The Einstein- Montefiore GCRC will serve a population in the Bronx and Westchester Counties of New York State totaling some 1.9 million people, half from minority racial and ethnic groups. The strong commitment of the two institutions to the GCRC initiative has provided new space and facilitated access to resources for patient-oriented research. The enthusiasm for the GCRC program is demonstrated by the participation of 44 investigators from a total of II departments--both clinical and basic science--who will be involved in the projects described in this application, bringing to bear over $14 million in federally-funded research support. These investigator- initiated projects involve a diverse range of human diseases such as diabetes, tuberculosis, Wilson's disease, liver disease, sickle cell anemia, polycystic kidney disease, systemic lupus erythematosus, infectious diarrhea, obesity, cardiovascular disease, impotence, cervical cancer, and dementia. The projects bring together interdisciplinary research which is principally NIH-funded but which lack adequate resources for clinical studies. The GCRC facilities are located on a single campus in the Bronx; the GCRC administrative, outpatient, sample processing laboratory, and biostatistical components will be located at the College of Medicine and the inpatient per diem admissions and special procedures units at the contiguous University Hospital. A large number of Centers and Shared Scientific Facilities will provide support to GCRC investigators. The Einstein GCRC will provide an environment to conduct human studies and to facilitate data acquisition, management, and analysis, and will encourage collaborations between basic and clinical scientists. Finally, the GCRC will serve as the centerpiece of the Institution's commitment to the training of young physician scientists. The Center's administration will include executive staff from the College of Medicine and Hospital, and the Center will be directed by an experienced group of investigators with previous GCRC experience, basic science expertise and strong independent scientific programs.