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MULTICENTER 34 WEEK STUDY OF INVINAVIR/NELFINAVIR IN HIV 1 SEROPOSITIVE PATIENTS

MULTICENTER 34 WEEK STUDY OF INVINAVIR/NELFINAVIR IN HIV 1 SEROPOSITIVE PATIENTS
Invinavir/Nelfinavir 在 HIV 1 血清阳性患者中的多中心 34 周研究
批准号：
6219274
负责人：
SHARON RIDDLER
金额：
$0.3万
依托单位：
UNIVERSITY OF PITTSBURGH AT PITTSBURGH
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6219274
关键词：
AIDS therapy HIV infections antiAIDS agent antiviral agents clinical research clinical trials combination chemotherapy drug screening /evaluation human immunodeficiency virus 1 human subject human therapy evaluation pharmacokinetics protease inhibitor

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中文摘要
翻译
这是一项平行的时间滞后的双组多剂量24周研究，旨在评估联合应用吲哚那韦1000 mg q12h和奈非那韦750 mg q12h的安全性和耐受性。此外，还将评估这两种药物的药代动力学以及该组合物的抗逆转录病毒活性。
英文摘要
This is a parallel time lagged 2 panel multiple dose 24 week study designed to evaluate the safety and tolerability of the coadministration of indinavir 1000 mg q12h and nelfinavir 750 mg q12h. Additionally, pharmacokinetics of both as well as the antiretroviral activity of the combination will be evaluated.
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