Droperidol and olanzapine as adjuncts to midazolam for the acutely agitated patient: a randomised clinical trial

无论是由于严重的精神疾病还是药物中毒，对急性焦虑症患者的管理都会导致急诊科资源的不成比例的使用。当一个人有伤害自己或他人的风险时，经常使用药物镇静。这项研究将确定当抗精神病药物(氟哌利多和奥氮平)与咪达唑仑(一种常用的镇静剂)一起使用时，是否比单独使用咪达唑仑的镇静更安全和有效。

Management of the acutely agitated patient, whether due to severe psychiatric illness or drug intoxication, results in a disproportionate use of Emergency Department resources. Drug sedation is frequently employed when an individual is at risk of harming themselves or others. This study will determine if antipsychotic drugs (droperidol and olanzapine), when added to midazolam (a commonly used sedative), is safer and more efficacious than sedation with midazolam alone.