CORE--RESOURCE FOR TUMOR TISSUE AND DATA

肿瘤组织和数据资源的目标是促进使用 在癌症研究中的人体组织，从而促进应用 在实验室里的发现，癌症的预防，早期发现， 预后和治疗。该资源是由博士于1975年成立。 丽塔·德莫普洛斯，并稳步增长。它完全由 这个国家卫生研究院的拨款我们最大的挑战是发展 它的多功能性，以应对不断变化的需求，其调查。 该资源提供的一些服务包括：1）纸巾 采购（在营养培养基中新鲜交付或在 液氮）; 2）Rita Demopoulos博士选择合适的 石蜡包埋肿瘤和对照组织，用于回顾性研究 免疫细胞化学、原位杂交和各种分子生物学 生物学研究。3)提供人口数据以及详细的 将研究结果与以下因素相关联所需的临床信息 临床参数; 4）快速识别新诊断患者 用于随机治疗临床试验的累积;和5）快速 为流行病学研究确定新诊断的患者， 登记贝尔维尤乳腺癌患者进入 综合乳房中心计算机化数据库。 每年使用这一资源的调查员人数最多时为55人 截至1997年6月30日的期间。637例新鲜组织和772例石蜡块 在1409年达到高峰的期间（1996年7月1日至1997年6月30日）， 标本我们88%的用户都有同行评审的赠款 也是癌症中心的成员

The goal of the Resource for Tumor Tissue and Data is to foster the use of human tissue in cancer research, thus, facilitating the application of findings in the laboratory to cancer prevention, early detection, prognosis and treatment. The Resource was established in 1975 by Dr. Rita Demopoulos and has grown steadily. It has been solely funded by this NIH Grant. Our greatest challenge has been to develop the versatility to respond the changing needs of its investigators. Some of the services provided by the Resource include: 1) Tissue procurement (delivered fresh in nutrient media or freshly frozen in liquid nitrogen); 2) Selection by Dr. Rita Demopoulos of appropriate paraffin embedded tumor and control tissues for retrospective immunocytochemistry, in situ hybridization, and various molecular biological studies. 3) Provision of demographic data as well as detailed clinical information needed for correlation of research findings with clinical parameters; 4) Rapid identification of newly diagnosed patients for accrual to randomized therapeutic clinical trials; and 5) Rapid identification of newly diagnosed patients for epidemiology studies and for registration of Bellevue breast cancer patients into the Comprehensive Breast Center computerized data base. The number of investigators per year using this resource peaked at 55 for the period ending 6/30/97. 637 fresh tissues nd 772 paraffin blocks were provided during the period (7/1/96-6/30/97) which peaked at 1409 specimens. Eighty-eight percent of our users have peer reviewed grants and are also Cancer Center members.