LOS ANGELES HIV PREVENTION TRIALS UNIT

本申请将在洛杉矶县建立一个艾滋病毒预防试验联盟（HPTC），该联盟将成为NIH艾滋病毒预防试验网络（HPTN）的一个下属单位，并将与该网络密切合作。洛杉矶HPTC将为HPTN带来以下四个团体之间强大的本地合作伙伴关系：1）社区倡导者和教育工作者，他们可以在历史上服务不足的社区建立对预防研究的支持2）以社区为基础的研究人员和流行病学家，具有与高风险人群合作的经验3）行为科学家和临床医生，能够设计和快速实施第一阶段，II和III行为和治疗预防和杀微生物剂试验，以及，4）基础病毒学家和免疫学家致力于确定和测量对艾滋病毒的保护性免疫的关键相关因素。洛杉矶HPTC是由来自四个学术机构（南加州大学、加州大学洛杉矶分校、加州州立大学、长滩和查尔斯R.德鲁医学和科学大学），为非洲裔美国人和拉丁美洲人服务的社区护理和预防团体，以及洛杉矶的同性恋和双性恋社区（帮助每个人（T.H.E.）诊所，AltaMed和同性恋中心）和艾滋病毒流行病学和预防研究专家。该联盟的目标是为促进对有效的行为、杀微生物和治疗干预措施的理解做出重大贡献，这些干预措施将减少艾滋病毒的传播，同时建立社区对预防研究的支持。

This application will establish in Los Angeles County a HIV Prevention Trials Consortium (HPTC) that will be a unit under and will work in close collaboration with the NIH HIV Prevention Trials Network (HPTN). The Los Angeles HPTC will bring to the HPTN a strong local partnership between the following four groups: 1) community advocates and educators who can build support for prevention research in historically underserved communities 2) community-based researchers and epidemiologists with experience working with high-risk populations 3) behavioral scientists and clinicians capable of designing and rapidly implementing Phase I, II and III behavioral and therapeutic prevention and microbicide trials, and, 4) basic virologists and immunologists committed to identifying and measuring the key correlates of protective immunity against HIV. The Los Angeles HPTC has been formed by bringing together community stakeholders and advocates, researchers from four academic institutions (University of Southern California, University of California at Los Angeles, California State University, Long Beach and the Charles R. Drew University of Medicine and Sciences), community-based care and prevention groups serving the African American and Latino, and gay and bisexual communities of Los Angeles (To Help Everyone (T.H.E.) Clinic, AltaMed, and the Gay and Lesbian Center) and experts in HIV epidemiology and prevention research. The goal of this consortium is to make significant contributions to advancing the understanding of effective behavioral, microbicidal and therapeutic interventions that will reduce HIV transmission while building community support for prevention research.