National Study of Risk Factors for Adolescent Drug Use

近年来，了解和预防青少年物质使用和其他健康风险行为的策略越来越多地体现在风险和保护因素框架中。 基于流行病学的预防方法植根于这一框架，旨在评估个人或群体的风险和保护因素水平，然后选择和实施将有效降低升高的风险因素和/或增强保护因素的具体策略。 虽然在过去二十年中，研究已经确定了许多相互关联的青少年药物使用风险因素，但很少有研究同时审查了具有全国代表性的大型样本的综合推定风险和因素。 由于这些研究在目标人群和样本量、测量和其他方法学特征方面存在差异，因此以往研究结果的整合受到阻碍。这项拟议的研究旨在通过对青少年家庭人口及其父母进行一项具有全国代表性的横断面调查，并在多个领域研究一套全面的假设风险因素，来促进我们对青少年物质使用风险因素的理解。 为此，我们将利用1999年全国家庭药物滥用调查（NHSDA）。 NHSDA的大样本将使研究人员能够评估风险/保护因素与广泛物质和物质使用阶段的物质使用之间的关系，并检查这些关系如何因年龄，性别，种族/民族和其他人口统计学变量而变化。多变量逻辑建模程序将应用于这些目的。 虽然1999年NHSDA的横截面性质排除了明确的评估时间顺序的变量内的关系进行调查，拟议的研究将提供一个强有力的实证基础上建立的存在，强度和鲁棒性之间的关联广泛的风险和保护因素和青少年物质使用行为。

Strategies for understanding and preventing adolescent substance use and other health risk behaviors have in recent years become increasingly couched in a risk and protective factor framework. Epidemiologically- based prevention approaches rooted in this framework seel to assess the levels of risk and protective factors in individuals or groups and then select and implement specific strategies that will effectively reduce elevated risk factors and/or enhance protective factors. Although research has identified numerous and interrelated risk factors for substance use among youth over the past two decades, very few studies have simultaneously examined comprehensive sets of putative risk and factors with large and nationally representative samples. The integration of findings from prior studies has been hampered by differences across these studies with respect to their target populations and sample sizes, measures, and other methodological features. The proposed study seeks to advance our understanding of risk factors for adolescent substance use by utilizing a single, nationally representative cross-sectional survey of the adolescent household population and their parents and examining a comprehensive set of hypothesized risk factors across multiple domains. We will utilize the 1999 National Household Survey on Drug Abuse (NHSDA) for this purpose. The large NHSDA sample will enable the investigators to assess the relationship between risk/protective factors and substance use for a broad range of substances and stages of substance use, and to examine how these relationships vary by age, gender, racial/ethnic group, and other demographic variables. Multivariate logistic modeling procedures will be applied for these purposes. Although the cross-sectional nature of the 1999 NHSDA precludes definitive assessment of temporal ordering of the variables within the relationships to be investigated, the proposed study will provide a strong empirical basis on which to establish the existence, strength, and robustness of the associations between an expansive set of risk and protective factors and adolescent substance use behaviors.