A non-inferiority trial of cytisine versus varenicline for smoking cessation.

通过现有的行为和药理学方法戒烟的长期戒烟率仍然很低，需要进一步的循证治疗来补充标准治疗。我们将进行一项大规模的试验，以证明金雀花碱与现有的伐尼克兰治疗相比的成本效益。这些发现将对医疗保健系统产生直接影响，金雀花碱如果有效，有可能挽救全球数百万人的生命。

Long-term quit rates via existing behavioural and pharmacological approaches to smoking cessation remain low and there is a need for further evidence-based treatments to complement standard treatment. We will conduct a large-scale trial to demonstrate the cost-effectiveness of cytisine compared to existing varenicline treatment. The findings will have direct health care system implications and cytisine, if effective, has the potential to save millions of lives globally.