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Prompt gamma Compton camera for proton therapy

Prompt gamma Compton camera for proton therapy
用于质子治疗的即时伽玛康普顿相机
批准号:
ST/M00791X/1
负责人:
Robert Speller
金额:
$14.93万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2015
资助国家:
英国
项目状态:
已结题
起止时间:
2015 至 --

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项目成果

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中文摘要
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英文摘要
Proton Beam Therapy is a type of radiotherapy, which uses a precision high-energy beam of particles to destroy cancer cells. The treatment is particularly suitable for complex childhood cancers, increasing success rates and reducing side- effects, such as deafness, loss of IQ and secondary cancers. It can also used to treat brain cancers and head and neck cancers. It is crucial that there is clear knowledge of the quantity of radiation required and also delivered to a patient during treatment. This proposal "Imaging of prompt gamma emissions during proton cancer therapy for geometric and dosimetric verification", aims to develop an optimised detector and methodology to allow real time verification of radiation delivery.This task is an essential part of the radiotherapy process, however this is significantly more challenging for protons than for high energy photons (which are utilised in existing facilities). The proposal brings together experts in radiation sensors from the University of Liverpool, imaging experts from University College London (UCL) and University College London Hospital (UCLH) and Radiation therapy professionals from the Clatterbridge Cancer Centre. UCLH will be the home of one of the two new proton therapy centres to be built in England, Clatterbridge houses the only existing proton therapy facility in the UK.
期刊论文(3)
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会议论文
Image reconstruction of prompt gamma emissions during proton cancer therapy for geometric and dosimetric verification
质子癌症治疗期间瞬发伽马发射的图像重建,用于几何和剂量验证
DOI: --
发表时间: 2016
期刊:
影响因子: --
作者: [Gutierrez A]
通讯作者: Gutierrez A
DOI: 10.1088/1748-0221/13/01/c01036
发表时间: 2018-01-01
期刊: JOURNAL OF INSTRUMENTATION
影响因子: 1.3
作者: [Gutierrez, A., Baker, C., Boston, A. J.]
通讯作者: Boston, A. J.
Optimisation of pulse shape discrimination using EJ299-33 for high energy neutron detection in proton beam therapy
使用 EJ299-33 优化质子束治疗中高能中子检测的脉冲形状辨别
DOI: 10.1088/1748-0221/12/11/c11033
发表时间: 2017
期刊: Journal of Instrumentation
影响因子: 1.3
作者: [Chung S]
通讯作者: Chung S
Pix3D - A 3D sample identification system combining X-ray imaging and diffraction based on a pixellated, energy dispersive detector.
  • 批准号:
    ST/P000088/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $45.58万
  • 财政年份:
    2016
  • 负责人:
    Robert Speller
  • 依托单位:
Sample identification system combining X-ray imaging and diffraction, based upon the use of a pixelated, energy resolving sensor
  • 批准号:
    ST/L00318X/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $13.74万
  • 财政年份:
    2014
  • 负责人:
    Robert Speller
  • 依托单位:
国内基金
海外基金
GABAAR/NMDAR功能耦合调控海马Gamma振荡介导咪达唑仑联合艾司氯胺酮抗谵妄的机制研究
  • 批准号:
    JCZRLH202600595
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2026
  • 负责人:
  • 依托单位:
gamma-经颅交流电联合iTBS改善阿尔兹海默症患者认知功能的临床随机对照研究
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  • 项目类别:
    省市级项目
  • 资助金额:
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    2025
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    刘军
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杏仁核-海马环路Gamma振荡的改变在OSA学习记忆中的作用机制探讨
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    --
  • 项目类别:
    面上项目
  • 资助金额:
    --
  • 批准年份:
    2024
  • 负责人:
    陈锐
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Vdelta2-T细胞外泌体疫苗携带IFN-gamma和TNF-alpha诱导抗原提呈细胞成熟并促进EBV肿瘤免疫应答的机制研究
  • 批准号:
  • 项目类别:
    省市级项目
  • 资助金额:
    15.0万元
  • 批准年份:
    2024
  • 负责人:
    王系伟
  • 依托单位: