SELF ASSEMBLED POLYMER THIN FILMS BOUND TO SOLID SURFACES: TISSUE ENGINEERING

该项目的目标是设计一个新的聚合物系列， 自发地在固体表面上组装的材料， 结合聚合物单层。 这些材料将用作表面 改性剂，为应用提供轮廓分明的表面 在细胞和组织工程、润滑、粘附和腐蚀中。 聚合物结构包括三种特定的元素， 1）已知的特定锚基团， 化学吸附到金属和氧化物表面，2）柔性聚合物骨架 其连接多个侧链，和3）一组官能团或 赋予聚合物膜功能特性的侧链。

The goal of this project is to design a family of new polymeric materials which spontaneously assemble on solid surfaces, forming bound polymer monolayers. The materials will be used as surface modification agents, presenting well-defined surfaces for applications in cell and tissue engineering, lubrication, adhesion, and corrosion. Polymer architectures comprising three specific elements which promote self-assembly are being used 1) specific anchor groups known to chemisorb to metal and oxide surfaces, 2) a flexible polymer backbone which links multiple side chains, and 3) a set of functional groups or side chains which impart a functional character to the polymer film.