CENTER ON TOBACCO USE SUSCEPTIBILITY AND INTERVENTION

拟议的TTURC反映了几个独特的优势。首先，该中心汇集了五位在烟草研究领域具有不同专业知识的杰出项目负责人(dr。Leslie, Janner, potin， Pechman和Tengs)。这些学者在药理学、神经科学、人类发展、社会与健康心理学、社区健康促进和卫生政策分析等各自的学科领域都取得了杰出的成就。这些科学家将合作确定动物尼古丁依赖和人类烟草易感性和使用的关键预测因素。合作的一个主要目标是建立一个烟草易感性和使用的共享概念模型，该模型可用于整合跨多个分析层面（即生物、行为、发育、人际和流行病学/社区层面）的实验结果，并将这些发现转化为干预策略(即药理学、行为、社会营销、以及卫生政策战略)，将对其公共卫生效力和成本效益进行评估。TTURC的第二个主要优势是其包含四个高度互动的核心，每个核心都旨在促进烟草易感性、使用和干预领域的成功跨学科合作。跨学科核心将实施结构化的活动来促进科学合作（例如，团队研讨会、务虚会），并根据跨学科研究的前因由、中间过程和科学成果的分类模型，对TIURC成员之间的合作进行系统的自我研究。信息学核心（由Shankle博士领导）将开发一些有价值的信息资源，包括一个共享的关系数据库，以促进跨多个TTURC项目的数据集和研究成果的整合，以及一个交互式的TTURC网站)，所有这些都旨在促进更有效的跨学科合作。Whitely和Fallon)整合了研究项目和跨学科和信息学核心中强调的理论和方法观点。它将提供广泛的跨学科培训机会，直接响应《青少年预防烟草倡议工作组报告》（1998年）中概述的培训优先事项。最后，行政核心将由博士共同领导。Leslie和Stokols，他们都有丰富的大学管理经验，并活跃在药理学、神经科学、社区健康促进、社会生态学和跨学科理论发展等领域。合作项目主任将监督教技会的互动活动，目的是促进项目团队成员、研究实习生和员工以及外部和内部咨询委员会成员之间有效的跨学科合作。

The proposed TTURC reflects several unique strengths. First, the Center brings together five eminent project leaders with diverse expertise in the field of tobacco research (Drs. Leslie, Janner, PotInn, Pechman, and Tengs). Each of these scholars has achieved distinction in their respective disciplines of pharmacology, neuroscience, human development, social and health psychology, community health promotion, and health policy analysis. These scientists will work collaboratively to identify key predictor of nicotine dependency in animals and tobacco susceptibility and use in humans. A major goal of the collaboration is to establish a shared conceptual model of tobacco susceptibility and use that can be used to integrate experimental findings across multiple levels of analysis (i.e., biological, behavioral, developmental, interpersonal, and epidemiological/community levels), and to translate these findings into intervention strategics (i.e., pharmacological, behavioral, social marketing, and health policy strategies) that will be evaluated for their public health efficacy and cost effectiveness. A second major strength of the TTURC is its incorporation of four highly interactive cores, each strategically designed to promote successful transdisciplinary collaboration in the field of tobacco susceptibility, use, and intervention. The Transdisciplinary Core will implement structured activities to foster scientific collaboration (e.g., team workshops, retreats), and also conduct a systematic self study of collaboration among members of the TIURC over a five-year period, based on a taxonomic model of the antecedents, intermediate processes, and scientific outcomes of transdisciplinary research. The Informatics Core (led by Dr. Shankle) will develop several valuable informational resources, including a shared relational data base to facilitate the integration of data sets and research findings across multiple TTURC projects and an interactive TTURC web site), all designed to promote more effective transdisciplinary collaboration The Career Development Core (co-directed by Drs. Whitely and Fallon) integrates the theoretical and methodological perspectives emphasized in the research projects and the Transdisciplinary, and Informatics Cores. It will afford a wide array of transdisciplinary training opportunities that are directly responsive to the training priorities outlined in the Report of the Working Groups of the Youth Tobacco Prevention Initiative (1998). Finally, the Administrative Core will be co-directed by Drs. Leslie and Stokols, both of whom have extensive university administrative experience and are active in the fields of pharmacology, neuro5cience, community health promotion, social ecology, and transdisciplinary theory development. The CO-PIs will oversee interactive activities of the TTURC with the goal of promoting effective transdisciplinary collaboration among the project team members research trainees and staff and members of the External and Internal Advisory Boards.