TAXONOMY AND DIAGNOSIS OF ADOLESCENT ALCOHOL USE DISORDERS

了解青少年酒精的性质、结构和过程 问题是有意义的病因和研究进展所必需的 这些问题的处理。然而，目前的病因学系统 酒精使用障碍在很大程度上是由研究和临床发展而来的 与成年人相处的经验。这项研究的主要目的是对比 酒精使用障碍的不同分类系统的有效性 适用于青少年。 该项目将利用所有参与PAARC临床研究的受试者 核心评估。样本中将含有大量的男性和女性 青少年。男女各有一半的人将被诊断为酗酒 虐待或依赖。没有酒精诊断的受试者将提供 广泛的饮酒和与酒精有关的问题。症状， 诊断、独立的问题措施以及酒精和药物使用将是 在基线和几次纵向随访时进行评估。这些设计 功能提供了对一系列问题的标准化评估 严重性，发展重点放在分期和进程上。措施 包括DSM结构化临床访谈(SCID)，独立 酒精依赖和心理社会功能障碍的测量，以及酒精 和毒品使用数据。SCID已适用于评估DSM-IV和ICD-10 症状和其他与青少年相关的问题领域，提供了 对这一人群的酒精症状进行全面评估。这个 的可靠性、协变性、诊断效率和严重程度权重 症状将会被确定。我们将研究哪些诊断标准是 最适合青少年使用。一段时间内的阶段和进程 酒精症状和紊乱将被确定。初步数据 建议一种青少年酗酒的新配方，定义为重度和 失控的饮酒伴随着相关的社会和人际问题。 这一定义的同时有效性和预测性有效性将是 与DSM-IV酒精滥用和ICD-10有害使用诊断进行对比。 其他分析将对比以下各项的同时和预测效度 对酒精依赖的不同定义。这项研究将产生 关于青少年酒精的发育和性质的重要信息 有问题。

Understanding the nature, structure, and course of adolescent alcohol problems is necessary for meaningful research progress on the etiology and treatment of these problems. However, current nosological systems for alcohol use disorders have largely developed from research and clinical experience with adults. The primary goal of this research is to contrast the validity of different taxonomic systems for alcohol use disorders when applied to adolescents. This project will utilize all subjects who participate in PAARC'S Clinical Core assessment. The sample will contain a large number of male and female adolescents. Half of each gender will have a DSM-IV diagnosis of Alcohol Abuse or Dependence. Subjects without an alcohol diagnosis will provide a broad range of drinking and alcohol-related problems. Symptoms, diagnoses, independent problem measures, and alcohol and drug use will be assessed at baseline and several longitudinal follow ups. These design features provide standardized assessment of problems across a range of severity, with a developmental emphasis on staging and course. Measures include the Structured Clinical Interview for the DSM (SCID), independent measures of alcohol dependence and psychosocial dysfunction, and alcohol and drug use data. The SCID has been adapted to assess DSM-IV and ICD-10 symptoms, and other problem domains relevant to adolescents, providing a comprehensive assessment of alcohol symptomatology in this population. The reliability, covariation, diagnostic efficiency, and severity weighting of symptoms will be determined. We will examine which diagnostic criteria are most appropriate for adolescents. The staging and course over time of alcohol symptoms and disorders will be determined. Preliminary data suggest a new formulation of adolescent alcohol abuse, defined by heavy and dyscontrolled drinking with associated social and interpersonal problems. The concurrent and predictive validity of this definition will be contrasted with DSM-IV Alcohol Abuse and ICD-10 Harmful Use diagnoses. Other analyses will contrast the concurrent and predictive validity of different definitions of alcohol dependence. This research will yield important information on the development and nature of adolescent alcohol problems.