TRANSMIT & RECEIVE COIL FOR 1H DECOUPLED 13C OR 31P DETECTION

一种用于在体质子去偶核磁共振的理想线圈结构 光谱学需要高灵敏度的13 C线圈以及 高效质子去耦线圈。 理想情况下，这些线圈应该具有 非常相似的敏感区域， 电磁相互作用 这些目标是通过一个新的 线圈设计利用正交1H线圈的优点， 将功率需求降低到原来的两倍，并将其与 线性极化13 C线圈，其性能损失可忽略不计， 频道 布置两个圆形1H线圈环（直径12 cm）， 在邻近7 cm直径的区域中产生正交场 13 C线圈由1/4”铜管制成。 部分重叠， 13 C线圈和每个单独的1H线圈以及 可以调整两个1H线圈，以使电磁干扰最小化， 所有线圈之间的耦合;这是在加载时执行的， 带有合适体模的实验室工作台（2.5L蒸馏水，100 ml 生理盐水）以及人腿。 所产生的 13 C线圈和任一1H线圈回路的噪声小于-20 dB， 各种加载情况（体模、人腿、人头）。 我们发现 所实现的隔离足以用于宽带去耦 而不需要增加另外的性能限制电路元件 作为一个线

An ideal coil configuration for in vivo proton decoupled NMR spectroscopy requires a highly sensitive 13C coil as well as an efficient proton decoupling coil. Ideally those coils should have very similar areas of sensitivity yet display no significant electromagnetic interaction. These goals were achieved with a new coil design that utilized the benefits of a quadrature 1H coil to reduce the power requirements up to two-fold and combined it with a linearly polarized 13C coil with negligible performance loss on either channel. Two circular 1H coil loops (12 cm diameter) were arranged to generate a quadrature field in the area adjacent to the 7 cm diameter 13C coil made from 1/4" copper tubing. Partial overlap between the 13C coil and each individual 1H coil as well as the overlap between the two 1H coils can be adjusted so as to minimize electromagnetic coupling among all the coils; this was performed while loaded on the laboratory bench with a suitable phantom (2.5l distilled water, 100 ml saline) as well as a human leg. The resulting coupling between the 13C coil and either of the 1H coil loops was less than -20 dB for various loading situations (phantom, human leg, human head). We found the achieved isolation to be sufficient for broad band decoupling without addition of further performance limiting circuit elements such as ??? lines.