RCMI CLINICAL RESEARCH INFRASTRUCTURE

要求支持临床研究中心的发展 (CRC)少数民族机构研究中心（RCMI） 临床研究基础设施倡议。制定一项CRC， 查尔斯德鲁医学与科学大学（德鲁大学）是 被视为扩大以病人护理为导向的研究的关键工具 为教师、研究员、内务人员和学生提供机会。历史上， 临床研究中心发挥了重要作用， 发展医学进步，从而为实践制定标准 医药和医疗保健的质量。没有CRC， 少数民族机构的发展造成了障碍， 致力于研究的临床研究人员的临界质量 这些健康问题不成比例地影响少数群体。在 此外，CRC的发展将促进学术合作 加州大学洛杉矶分校医学院 （ACLU）和ACLU附属机构和德鲁大学，从而 加强各机构的临床研究能力。 德鲁医院以病人护理为导向的研究活动有所增加 在过去的五年里。目前有6个考绩制度供资 临床研究，代表医学系， 外科，精神病学和麻醉学，这将是加强了对- 研究中心CRC。为了发展更广泛的临床活动， 允许形成一支具有竞争力的活跃的研究教师队伍 关于校外供资，要求为以下3个试点项目提供支助 研究项目：1）血管紧张素转换酶（ACE）对血管内皮细胞的影响 抑制糖尿病视网膜病变的进展; 2）类固醇 有支气管肺发育不良风险的早产儿的治疗; 3)Yq微缺失与男性不育总而言之， 该应用包括： 1.开发基础设施，以促进德鲁的临床研究 大学 2.通过增强核心实验室的激素和 放射免疫分析能力。 3.开展与健康有关的试点调查研究， 少数民族人口。 4.增加校外资助的临床研究者的数量。 5.为了鼓励德鲁大学教师之间的合作研究， Harbor-ACLU和ACLU 6.开设“临床研究的基础科学”讲座 系列.

Support is requested for the development of a Clinical Research Center (CRC) through the Research Center for Minority Institutions (RCMI) clinical research infrastructure initiative. The development of a CRC at Charles Drew University of Medicine and Science (Drew University) is viewed as a critical tool for expanding patient care oriented research opportunities for faculty, fellows, housestaff and students. Historically, clinical research Centers have played an influential role in the development medical advances, thereby setting standards for the practice of medicine and the quality of health Care. The absence of CRC's at minority institutions has created a barrier for the development of a critical mass of clinical research faculty dedicated to the investigation of those health issues that disproportionately affect minorities. In addition, the development of a CRC would foster scholarly collaboration between the University of California, Los Angeles, School of Medicine (ACLU) and ACLU-affiliated institutions and Drew University, thereby enhancing the clinical research capabilities of each institution. Patient care oriented research activities have increased at Drew University over the last five years. There are presently 6 PAS funded clinical research studies, representing the departments of Medicine, Surgery, Psychiatry and Anesthesiology, that would be enhanced by an on- site CRC. In order to develop a greater breadth of clinical activities and allow formation of a cadre of active research faculty who are competitive for extramural funding, support is requested for the following 3 pilot projects: 1)The Effects of Angiotensin Converting Enzyme (ACE)on the Inhibition of the Progression of Diabetic Retinopathy; 2) Steroid Treatment in Premature Infants at Risk for Bronchopulmonary Dysplasia; and 3) Yq Microdeltetions and Male Infertility. In summary, specific goals of this application include: 1. To develop an infrastructure to facilitate clinical research at Drew University. 2. To expand the Core laboratory by enhancing its hormone and radioimmunoassay capabilities. 3. To initiate pilot investigative studies related to the health of minority populations. 4. To increase the number of extramural funded clinical investigators. 5. To encourage collaborative research between faculty at Drew University, Harbor-ACLU and ACLU. 6. To develop a "Basic Science Foundations for Clinical Research" lecture series.