Clinical Research Training Program in NeuroOncology

我们建议在麻省总医院开展临床神经肿瘤学的多学科研究培训计划。这个为期两年的项目的主要目标是培养能够在脑肿瘤生物学和实验治疗学之间提供关键桥梁的内科科学家。为了实现这一目标，培训计划强调临床研究方法，癌细胞生物学和癌症药理学的教学课程，以及导师监督的实验室和临床研究经验。参加该培训计划的所有临床和实验室导师都具有丰富的神经肿瘤学研究和培训经验，为对转化研究感兴趣的学员提供了极好的资源。所有受训人员还将获得所有项目的高级生物统计和计算支助。由项目主管领导的咨询委员会将监督培训项目。除了麻省总医院的临床和基础科学研究设施外，参与机构还包括布里格姆妇女医院和达纳-法伯癌症研究所。候选人将包括完成神经病学，神经外科，内科肿瘤学和放射肿瘤学临床培训的医生。来自这些学科的合格申请者可以从现有和发展的来源中获得。每位受训者将有专门的两年研究和培训时间，承担最少的临床责任。每年申请4个博士后职位，为期5年，每位受训者承诺进行两年的研究。申请人将通过项目和个别教师的积极招聘来选择。我们相信，拟议的培训计划利用现有的优秀导师和一流的培训设施，并将有能力在神经肿瘤学方面培养出富有成效的临床医生科学家。

We propose a multidisciplinary research training program in clinical neuro-oncology based at the Massachusetts General Hospital. The primary objective of this two year program is to train physician- scientists capable of providing a critical bridge between brain tumor biology and experimental therapeutics. In order to achieve this objective the training program emphasizes a didactic curriculum in clinical research methodology, cancer cell biology and cancer pharmacology as well as mentor-supervised laboratory and clinical research experience. All clinical and laboratory mentors participating in this training program have extensive experience in neuro-oncology research and training and provide an excellent resource for trainees interested in translational research. All trainees will also have access to senior biostatistical and computing support on all projects. An advisory committee headed by the program director will oversee the training program. In addition to clinical and basic science research facilities at the Massachusetts General Hospital participating institutions include the Brigham and Women's Hospital and the Dana- Farber Cancer Institute. Candidates will include physicians completing clinical training in neurology, neurosurgery, medical oncology and radiation oncology. A qualified pool of applicants from these disciplines can be expected from existing and developing sources. Each trainee will have a dedicated two- year block for research and training with minimal clinical responsibilities. Four postdoctoral positions are requested per year for five years with each trainee making a two year commitment to investigation. Applicants will be selected through active recruitment by the program and individual faculty. We believe that the proposed training program capitalizes on an existing group of outstanding mentors and superb training facilities and will capability to produce productive clinician scientists in neuro-oncology.