EXPANSION OF MUTIDISCIPLINARY RES CTR: HIV-1 PTT SEQUENCE, HIV VACCINE

关于艾滋病描述(由申请人提供)：男男性接触者建议扩大其MRC。这一扩展将使研究所能够提供额外的空间，以容纳神经科学研究所(NI)和临床研究中心(CRC)研究人员增加的研究努力。MSM的生物医学和临床研究项目针对的是对少数民族和其他医疗服务不足的人群造成不成比例影响的疾病。该机构拥有NI、心血管研究所、预防研究中心、CRC和太空医学中心。此外，该研究所还拥有两个少数民族机构研究中心(RCMI)计划、一个少数民族生物医学研究支持(MBRS)计划和133个个人研究奖项，其中包括19个R01奖项。目前的研究经费总额为34,185,688美元，研究所2002财政年度从联邦和州来源获得的赠款和合同总额为70,879,499美元。MSM已经制定了一项全面的计划，以满足NI和CRC的调查人员对额外研究空间的需求。该计划有以下目标和具体目标：1)扩大MSM NI和CRC的研究力度；2)建设20,921平方英尺。英国《金融时报》(3)在扩建的基础上，增加实验室和专用室；4)在扩建的地下室内，建立一个用于存放研究对象医疗记录的安全区域，并设立一个动物笼子和床上用品储存区；5)加强MSM吸引更多研究项目的能力，包括R01；以及6)允许招聘更多从事前沿研究的科学家。

Regarding AIDS DESCRIPTION (provided by applicant): The MSM proposes to expand its MRC. This expansion will allow the Institution to provide additional space to accommodate increased research efforts of investigators of the Neuroscience Institute (NI) and the Clinical Research Center (CRC). MSM's biomedical and clinical research programs address diseases that disproportionately affect minority and other medically underserved populations. The Institution houses the NI, Cardiovascular Research Institute, Prevention Research Center, CRC and Space Medicine Center. Additionally, the Institution has two Research Centers in Minority Institutions (RCMI) Programs, a Minority Biomedical Research Support (MBRS) Program and 133 individual research awards, including 19 R01 awards. The current amount of research funds total $34,185,688, and the Institution has a total of $70,879,499 in grants and contracts from federal and state sources for FY 2002. MSM has developed a comprehensive plan to address the need for additional research space for investigators in the NI and the CRC. The plan has the following goal and specific aims: 1) expand research efforts of MSM's NI and CRC; 2) construct a 20,921 sq. ft. addition (three stories and a basement) to the MRC with an outcome of increasing the research portfolios of the two units; 3) provide, within the addition, an increase of laboratory and specialty rooms for research; 4) create, within the basement of the addition, a secure area for storage of medical records of study subjects and an area for the storage of animal cages and bedding; 5) enhance MSM's ability to attract additional research projects, including R01s; and 6) allow for the recruitment of additional scientists engaged in cutting-edge research.