VISION RES LAB: HERPETIC KERATIC, CORE PIGMENT GENES, RETINITIS PIGMENTOSA

描述（由申请人提供）：自1995年以来，威斯康星州医学院是美国第四大增长最快的主要研究型医学院，由美国国立卫生研究院（NIH）资助。该机构目前在125所报告的学校中排名第33百分位。一个长期目标是为美利坚合众国公民的健康做出重大贡献，如“2010年健康人”所述。“提高贡献的一种手段是雇用研究人员，他们正在进行NIH资助的高质量研究，从而继续提高排名。该机构正处于制定战略计划的阶段，其目标是为今后五年（2002-2007年）的增长确定道路。一个主要的重点领域是神经科学，其中包括视觉研究。近期目标是更新和扩大现有设施，目的是增加NIH资助的研究人员进行神经科学相关研究和培训的数量。该项目的具体目标是建立更多的研究实验室，以支持作为神经科学倡议的一部分的视觉研究工作的扩展。 拟议将眼科研究所的第七层从临床和行政空间改为供三名研究人员使用的研究实验室和相关的核心支助实验室。眼科研究所八楼已有20年历史的研究实验室将被改造，因为最初的建筑设计无法预测扩大研究人员的具体实验室需求。额外空间的总收益是至少增加两名首席调查员（PI）和纠正现有设施的不足之处。此外，这将增加独立的实验室空间，以容纳视觉研究核心资助（P30-EY 01931）的模块，该模块支持12名NIH资助的研究人员的研究工作。

DESCRIPTION (provided by applicant): The Medical College of Wisconsin is the nation's fourth fastest rising major research medical school in terms of extramurally funded awards by the National Institutes of Health (NIH) since 1995. The Institution now ranks at the 33rd percentile of the 125 schools reporting. One long-term goal is to contribute significantly to the health of the citizens of the United States of America as described in "Healthy People 2010." A means to enhance contribution is to hire research faculty that are conducting research of the quality funded at the level of NIH thus continuing to improve ranking. The Institution is at a point of evolution of a strategic plan where the goals are set to establish path for the next five years of growth (2002-2007). One major area of focus is neuroscience, which includes vision research. The immediate objective is to update and expand existing facilities with the aim of increasing the number of NIH-funded investigators doing neuroscience-related research and training. The specific aim of this project is to construct more research laboratories that are needed to support expansion of vision research efforts as part of neuroscience initiative. It is proposed to convert the seventh floor of the Eye Institute from clinical and administrative space to research laboratories for three investigators and associated core support laboratories. The 20-year-old research laboratories on the eighth floor of the Eye Institute will be remodeled, since the original building design could not have forecast the specific laboratory needs of expanding research staff. The total gain of additional space is for at least two more Principal Investigators (PIs) and correct deficiencies in the current facility. Furthermore, this will add discrete laboratory space to house the modules of Core Grant for Vision Research (P30-EY01931) which supports the research efforts of 12 NIH-funded investigators.