EPIDEMIOLOGY OF DIABETES INTERVENTION AND COMPLICATIONS

糖尿病控制和并发症试验（DCCT）结果于1993年发布（NEJM 1993年9月）。 这项多中心研究证明，强化血糖控制可显著降低微血管病变的风险（视网膜病变76%，肾病54%，神经病变60%）。糖尿病干预和并发症的流行病学（EDIC）是DCCT队列的十年流行病学研究。 本研究将通过每年对每例受试者进行研究，重点关注大血管和肾脏并发症的发生率。 这项研究将提供有关糖尿病并发症长期病程的有价值的信息。 将研究已确定和推定风险因素之间相互作用的影响，包括糖尿病治疗和微血管、神经和大血管长期并发症的血糖控制水平。 预计新资料的传播将在计划的后续行动结束之前开始，重要结果将及时公布。

The Diabetes Control and Complications Trial (DCCT) results were released in 1993 (NEJM September 1993). This multicenter study proved that intensive control of blood glucose dramatically reduced the risk for microangiopathy (retinopathy 76%, nephropathy 54%, neuropathy 60%). The Epidemiology of Diabetes Interventions and Complications (EDIC) is a ten year epidemiological study of the DCCT cohort. The study will focus upon the incidence of macrovascular and renal complications by studying each participant on an annual basis. This study will provide valuable information regarding the long-term course of the complications of diabetes in a carefully characterized study population. The effects of an interaction between established and putative risk factors, including diabetes treatment and level of glycemic control for microvascular, neurologic and macrovascular long-term complications will be studied. It is anticipated that the dissemination of the new information will begin well before the planned termination of follow-up and that important results will be published in a timely fashion.