HOME BASED MODERATE EXERCISE FOR BREAST CANCER PATIENTS

描述：创新的治疗方法，为日益增长的康复 癌症幸存者的数量是迫切需要的。 的乳腺癌患者 有完成癌症治疗的经验 心理困扰（例如，焦虑、抑郁、身体意象差），以及 疲劳和体重增加的身体症状可能持续数年 后处理。 随着生存率的提高，这些心理社会因素 困难更加突出。 调查人员建议提供 早期乳腺癌幸存者的创新治疗方案， 改善一些伴随的生理和心理症状 癌症诊断和治疗，并促进恢复生活任务。 在其他人群中，运动参与已被证明会减少 情感困扰，改善身体形象，增加授权感， 减少疲劳和体重增加。 本研究旨在探讨以家庭为基础的温和的可行性 乳腺癌幸存者的锻炼计划，以及这些 妇女可以从参加这样的方案中获益。 一百 34名患有早期乳腺癌（0、I和II期）的女性 在过去两年内确诊），已完成手术和辅助治疗 治疗将被邀请参加。 受试者将被随机分配至 12-一周的家庭锻炼计划或接触控制条件。 参与者将被要求完成标准化的锻炼措施， 情绪、生活质量、身体症状、身体意象和应对 治疗12周、6个月和9个月（3个月和6个月随访）。 运动参与度将通过自我报告和Caltrac进行测量 加速度计 将在治疗前和治疗后进行12分钟步行试验， 12周的时候。 协方差分析将用于评估治疗 影响和回归分析将用于确定哪些类型的 患者受益于这一独特的癌症康复计划。 通过评估以家庭为基础的锻炼计划对运动质量的影响， 癌症幸存者的生活和情绪，这项研究可以作为一个前兆， 研究运动对生活质量和癌症的长期影响 复发 这项研究还提出了一种有趣的可能性， 阐明运动对激素和免疫系统的生理影响 乳腺癌的发病机制

DESCRIPTION: Innovative treatments for the rehabilitation of the growing number of cancer survivors are sorely needed. Breast cancer patients who have completed medical treatment for cancer experience considerable psychological distress (e.g., anxiety, depression, poor body image), and physical symptoms of fatigue and weight gain that can last several years post-treatment. With increased survival rates, these psychosocial difficulties have become more salient. The investigators propose to offer early-stage breast cancer survivors an innovative treatment program to ameliorate some of the physical and psychological symptoms that accompany cancer diagnosis and treatment, and to facilitate resumption of life-tasks. Exercise participation in other populations has been shown to reduce affective distress, improve body image, increase sense of empowerment, and reduce fatigue and weight gain. This study proposes to examine the feasibility of a home-based moderate exercise program among breast cancer survivors and the benefits that these women could gain from participating in such a program. One hundred and thirty-four women with early-stage breast cancer (Stages 0, I and II diagnosed within the past two years) who have completed surgery and adjuvant therapy will be invited to participate. Subjects will be randomized to a 12-week home-based exercise program or a contact control condition. Participants will be asked to complete standardized measures of exercise, mood, quality of life, physical symptoms, body image and coping before treatment, at 12 weeks, 6 months and 9 months (3 and 6 month follow-ups). Exercise participation will be measured by self-report and by Caltrac accelerometers. A 12-minute walk test will be conducted at pretreatment and at 12 weeks. Analyses of covariance will be used to assess treatment effects and regression analyses will be used to determine which types of patients benefit from this unique cancer rehabilitation program. By evaluating the effects of a home-based exercise program on quality of life and mood in cancer survivors, this study can serve as a precursor to examining the long-term effects of exercise on quality of life and cancer recurrence. This study also raises the intriguing possibility of elucidating the physiological effects of exercise on hormonal and immune mechanisms involved in breast cancer.