课题基金 / 基金详情

PEDIATRIC ONCOLOGY GROUP

PEDIATRIC ONCOLOGY GROUP
儿科肿瘤组
批准号:
6341799
负责人:
SUSAN L. COHN
金额:
$14.15万
依托单位国家:
美国
项目类别:
财政年份:
1978
资助国家:
美国
项目状态:
已结题
起止时间:
1978-12-01 至 2002-12-31
关键词:
6 thiopurine Ewing's tumor Hodgkin's disease Wilms' tumor XomaZyme acivicin acute leukemia acute lymphocytic leukemia acute myelogenous leukemia adolescence (12-20) antineoplastics asparaginase astrocytoma biological response modifiers bone marrow transplantation brain neoplasms cancer registry /resource cancer risk central nervous system neoplasms child (0-11) chronic myelogenous leukemia cis platinum compound clinical research clinical trial phase I colony stimulating factor combination cancer therapy combination chemotherapy cooperative study cyclophosphamide cyclosporines cytosine arabinoside daunorubicin deferoxamine deoxycoformycin doxorubicin drug screening /evaluation enalapril ependymoma etoposide fazarabine fluorouracil germ cell neoplasms glioma hepatoblastoma hepatocellular carcinoma human genetic material tag human immunodeficiency virus 1 human subject human therapy evaluation human tissue ifosfamide interferons interleukin 2 medulloblastoma melphalan metastasis methotrexate mitoxantrone molecular oncology neoplasm /cancer chemotherapy neoplasm /cancer classification /staging neoplasm /cancer epidemiology neoplasm /cancer genetics neoplasm /cancer immunology neoplasm /cancer immunotherapy neoplasm /cancer pharmacology neoplasm /cancer radiation therapy neoplasm /cancer relapse /recurrence neoplasm /cancer surgery neuroblastoma nonHodgkin's lymphoma osteosarcoma paclitaxel pediatric pharmacology podophyllin prednisone retinoate rhabdomyosarcoma tissue resource /registry topotecan trimetrexate vincristine

项目摘要

项目成果

SUSAN L. COHN的其他基金

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中文摘要
翻译
该项目的目标是招收癌症儿童参加 临床试验,开展临床试验和生物学研究 儿童癌症的行为,并改善和评估这种疾病- 参加这些临床试验的患者的免费存活期。 为了实现这些目标,儿科协会的成员机构 肿瘤学小组(POG)每两年召开一次会议,讨论、开发和实施 最常见的儿童恶性肿瘤的临床试验和供应 适当材料或组织的参考研究实验室 对这项研究是必要的。 自1989年以来,CMH一直是POG的成员机构之一,他是 实际参与了癌症儿童到临床的收益 审判。CMH的教职员工也参与了研究的协调 作为首席调查员或联合调查员。这些协议 POG 9443、POG 9240/41/42、POG 9135/6、POG 9410、NTWS#5。 参与POG内的行政活动包括POG 主席,POG首席执行官,神经母细胞瘤负责人 神经母细胞瘤骨髓移植学会会长--生物委员会 工作组和下列委员会的成员:非 霍奇金淋巴瘤,神经母细胞瘤,骨髓移植,霍奇金 疾病、新急性淋巴细胞白血病、肾母细胞瘤、护理、外科手术、放射治疗和 病理学学科。
英文摘要
The objectives of this project are to enroll children with cancer in clinical trials, to develop clinical trials and study the biologic behaviors of childhood cancer, and to improve and evaluate the disease- free survival of patients enrolled in these clinical trials. In order to achieve these goals, the member institutions of the Pediatric Oncology Group (POG) meet biannually to discuss, develop, and implement clinical trials for the most common childhood malignancies and to supply the reference research laboratories of the proper material or tissue necessary for the research. Since 1989, CMH has been one of the member institutions of POG who is actually involved in the accrual of children with cancer to clinical trials. CMH's faculty is also involved in the coordination of studies either as the Principal Investigator or co-Investigator. These protocols are POG 9443, POG 9240/41/42, POG 9135/6, POG 9410, NTWS #5. Participation in administrative activities within POG include the POG Chairperson, the POG Executive Officer, the Head of the Neuroblastoma Biology Committee, the Head of the Neuroblastoma Bone Marrow Transplant Working Group, along with members of the following committees: Non- Hodgkin's Lymphoma, Neuroblastoma, Bone Marrow Transplantation, Hodgkin's Disease, New ALL, Wilms' Tumor, Nursing, and Surgery, Radiotherapy, and Pathology Disciplines.
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