NOVEL, FAST, RELIABLE&INEXPENSIVE RADIATION DOSIMETER
NOVEL, FAST, RELIABLE&INEXPENSIVE RADIATION DOSIMETER
批准号:
6310476
负责人:
Gavin James Braithwaite
金额:
$9.86万
依托单位国家:
美国
项目类别:
财政年份:
2001
资助国家:
美国
项目状态:
已结题
起止时间:
2001-08-01 至 2002-03-31
中文摘要
描述(申请人摘要逐字):在这份SBIR第一阶段建议书中,我们
将开发一种新的辐射剂量测量技术用于电离
辐射产业。辐射经常被用来消毒生物医学。
聚合物,并通过交联化改善这些植入物的性能。
聚合物辐射通常需要超过200kGray的剂量水平。电子束
因此,操作员需要具有此范围和快速响应时间的剂量计
动态调整剂量率。最常用的光致变色染料
50千格雷饱和的剂量测量系统,通常需要5-6小时才能稳定下来,以及
显示出衰老。利用聚(乙烯)中的辐解反应
在接受电离辐射的情况下,辐射剂量的可靠标记可以
获得。我们的方法集中在一种特定的辐射分解反应上
具有辐射剂量,并且很容易用红外吸收来测量。这
提案将涉及设计和制造足够小的原型,
而且很简单,不需要特殊培训就可以在辐射设施中使用。这个
薄剂量学目标将是柔性的(因此是可整合的)、有弹性的、
耐受污染和损坏(因此非常适合工业
实验室或生产车间的应用程序),并将做出回应
时间大约为几分钟。他们还将对衰老免疫,并拥有
比其他目前的剂量学技术高得多的剂量范围。
建议的商业应用:
建议的剂量计设计将提供一种简单、低成本的技术,能够
取代并改进当前最先进的辐射剂量测量方法。
该阅读器只需很少的培训或无需培训即可使用。因此,它将在任何
必须具有快速响应剂量计的辐射设施(例如需要
可变剂量),在高剂量应用(如整形外科植入物制造)中,
需要定向照射的应用(如金属丝涂层行业)和
表面污染可能成为问题的环境。
英文摘要
DESCRIPTION (Applicant's abstract verbatim): In this SBIR phase I proposal, we
will develop a new radiation dosimetry technique for use in the ionizing
radiation industry. Radiation is frequently used to sterilize biomedical
polymers, and improve through crosslinking, the properties of these implants.
Polymer irradiation often requires dose levels beyond 200 kGray. Electron beam
operators thus need dosimeters with this range and fast response times for
on-the-fly dose rate adjustment. Photochromic dyes, the most commonly used
dosimetry system, saturate at 50 kGray, often take 5-6 hours to stabilize, and
show aging. By making use of the radiolytic reactions in poly(ethylene)
undergoing ionizing radiation, a reliable marker for radiation dose can be
obtained. Our approach focuses on a specific radiolytic reaction that scales
with radiation dose, and is easily measured with infrared absorption. This
proposal will involve the design and fabrication of a prototype small enough,
and simple enough, to use at a radiation facility with no special training. The
thin dosimetry targets will be flexible (and therefore conformable), resilient,
tolerant of contamination and damage (therefore ideal for industrial
applications in laboratories or on production floors) and will have a response
time on the order of minutes. They will also be immune to aging and have
considerably higher dosage ranges than other current dosimetry techniques.
PROPOSED COMMERCIAL APPLICATION:
The proposed dosimeter design will provide a simple, low cost, technique capable of
replacing, and improving on, current state-of-the-art radiation dosimetry approaches.
The reader will be useable with little or no training. It will therefore be invaluable in any
radiation facility that must have fast response dosimeters (such as beam-lines requiring
variable doses), in high dose applications (such as orthopaedic implant fabrication), in
applications requiring directional irradiation (such as the wire coating industry) and in
environments where surface contamination may be an issue.
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会议论文
Degradable hydrogel for retinal tamponade (phase 2)
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批准号:10219260
-
项目类别:
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资助金额:$29.64万
-
财政年份:2020
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负责人:Gavin James Braithwaite
-
依托单位:
Degradable hydrogel for retinal tamponade (phase 2)
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批准号:9908974
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项目类别:
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资助金额:$29.61万
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财政年份:2020
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负责人:Gavin James Braithwaite
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依托单位:
Degradable hydrogel for retinal tamponade
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批准号:9255604
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项目类别:
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资助金额:$22.44万
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财政年份:2017
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负责人:Gavin James Braithwaite
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依托单位:
Injectable, biocompatible poly (vinyl alcohol) hydrogels for tissue bulking
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批准号:7747226
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项目类别:
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资助金额:$9.83万
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财政年份:2009
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负责人:Gavin James Braithwaite
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依托单位:
An injectable biocompatible hydrogel nucleus pulposus replacement
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批准号:7744555
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项目类别:
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资助金额:$7.67万
-
财政年份:2009
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负责人:Gavin James Braithwaite
-
依托单位:
海外基金