Ecto-nucleoside triphosphate diphosphohydrolases of Leishmania: Role in virulence and potential as antimicrobial targets
Ecto-nucleoside triphosphate diphosphohydrolases of Leishmania: Role in virulence and potential as antimicrobial targets
批准号:
nhmrc : 567048
负责人:
Dr Fiona Sansom
金额:
$20.98万
依托单位国家:
澳大利亚
项目类别:
Early Career Fellowships
财政年份:
2009
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2009-01-01 至 2014-12-31
中文摘要
利什曼病是一种严重的疾病,影响全世界数百万人,特别是在发展中国家。这种疾病是由许多种寄生虫引起的,目前的治疗方案并不理想。这项研究旨在针对寄生虫产生的某些蛋白质,并确定这些蛋白质在引起疾病中的作用。此外,这项研究将确定新的药物,将阻止这些寄生虫蛋白,并可能有助于新的疗法,这种严重的疾病。
英文摘要
Leishmaniasis is a serious disease that affects millions of people worldwide, particularly in developing countries. The disease is caused by a number of species of parasites, and current treatment regimes are not ideal. This research aims to target certain proteins produced by the parasite and define the role of the proteins in causing disease. Furthermore this research will identify new drugs that will block these parasite proteins and may contribute to new therapies for this serious disease.
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会议论文
Identifying metabolic pathways in Leishmania parasites and their host cells required for virulence
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批准号:nhmrc : 1059545
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项目类别:Project Grants
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资助金额:$65.95万
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财政年份:2014
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负责人:Dr Fiona Sansom
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依托单位:
Dissecting the molecular basis of Leishmania pathogenesis
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批准号:nhmrc : GNT1059545
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项目类别:Project Grants
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资助金额:$63.4万
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财政年份:2014
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负责人:Dr Fiona Sansom
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依托单位:
国内基金
海外基金
微波技术合成核苷类化合物的新方法研究
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批准号:20372018
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项目类别:面上项目
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资助金额:23.0万元
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批准年份:2003
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负责人:渠桂荣
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依托单位: