Adherence Intervention--Late Middle-Aged /Older Adults

描述（由申请人提供）：越来越多的人生活在 艾滋病毒/艾滋病患者年龄在50岁或以上。 这些中老年人中的许多人 人们报告说，很难严格遵守抗逆转录病毒疗法 养生法 这一点很重要，因为坚持复杂的艾滋病毒 药物治疗方案对于实现和维持改善的健康至关重要 结果。 然而，迄今为止，艾滋病毒依从性干预措施并没有特别 针对这个年龄段。 量身定制的干预措施，旨在满足 中年晚期和老年人的需求迫切需要。我们 建议设计和试点测试一项实验性干预措施， 中老年人坚持抗逆转录病毒治疗的情况 艾滋病毒携带者 干预措施的制定将遵循 行为改变和多成分干预的跨理论模型 将动机访谈技术与行为访谈相结合的策略 技能培训。 拟议的调查将分四个阶段进行 在两年的研究期间。 一系列的规划和发展 活动将包括：（1）与中年后期和 评估服用抗逆转录病毒药物的老年人的依从性问题， 干预偏好;（2）设计和测试可行性， 个体和群体依从性干预的可接受性 （3）年龄在50岁以上的艾滋病病毒感染者; 干预效果的试点测试;（4）编制干预手册 这些材料将构成随后提出的全面建议的基础。 实验干预的随机临床试验。 有很大 需要有效的依从性干预措施和可行的方法， 艾滋病病毒感染者。开发量身定制的 旨在提高抗逆转录病毒治疗技能和积极性的干预措施 50岁及以上的艾滋病病毒感染者坚持服药将有助于 满足这一需求。 这一规划项目构成了下一阶段的研究 必须改善中晚期抗逆转录病毒治疗的依从性 和老年艾滋病毒感染者。

DESCRIPTION (provided by applicant): A growing number of persons living with HIV/AIDS are aged 50 or older. Many of these late middle-aged and older persons report difficulty maintaining strict adherence to antiretroviral regimens. This is important because consistent adherence to complex HIV medication regimens is critical for achieving and sustaining improved health outcomes. However, HIV adherence interventions to date have not specifically targeted this age group. Tailored interventions designed to meet the unique needs of late middle-aged and older adults are urgently needed. We are proposing to design and pilot test an experimental intervention for increasing adherence to antiretroviral treatment among late middle-aged and older persons living with HIV. Intervention development will be guided by the transtheoretical model of behavior change and multi-component intervention strategies combining motivational interviewing techniques with behavioral skills training. The proposed investigation will be conducted in four stages over the two-year study period. A sequence of planning and developmental activities will include: (1) conducting focus groups with late middle-aged and older persons taking antiretroviral medications to assess adherence issues and intervention preferences; (2) designing and testing the feasibility and acceptability of individual-level and group-level adherence intervention formats for persons living with HIV who are 50 years of age or older; (3) pilot testing of intervention efficacy; and (4) preparing intervention manual materials which will form the basis for a subsequent proposal of a full-scale randomized clinical trial of the experimental intervention. There is a great need for effective adherence interventions and feasible methods for delivering them to underserved HIV infected populations. Development of a tailored intervention designed to enhance skills and motivation for antiretroviral adherence among persons aged 50 and older living with HIV AIDS will help address this need. This planning project constitutes the next phase of study necessary to improve antiretroviral treatment adherence in late middle-aged and older persons living with HIV.