MODERATE ALCOHOL USE--THE HETEROGENEITY OF ABSTENTION

申请人摘要：拟议项目的目的是确定， 戒酒者有更高的患病率的身体和精神疾病相比， 轻度至中度饮酒者，并在戒酒者中，确定是否 在身体和精神疾病的流行率方面存在差异。 社会人口统计指标、生活方式和种族/文化差异将 也可以检查戒酒者和轻度至中度酒精消费者。 到 为此，一个具有全国代表性的数据集，国家纵向 酒精流行病学调查将用于：（1）测量酒精使用情况， （2）饮酒的频率和饮酒量，（2）区分那些 基于健康、吸烟、种族和社会地位的差异， （3）在弃权者中确定是否有 不同类型的戒酒者患心脏病的风险差异;从不生病 饮酒者，健康的从不饮酒者，以前的轻度，中度，重度饮酒者， （4）在饮酒者中确定是否有 不同类型的戒酒者患抑郁症的风险差异，（5）确定 戒酒者比不戒酒的人有更高的抑郁/情绪问题 在控制社会人口统计学变量、种族和 身体疾病，以及（6）确定戒酒者是否有更高的心脏水平 疾病，与那些不弃权。 从这些活动中获得的信息将用于两个相关的目的： 增加我们对预防相关因素的理解，特别是 年龄、性别和种族之间的差异。 第二，提高我们的能力 将戒酒者分为病因学上有意义的类别， 适度饮酒与健康 通常是适度饮酒者，他们也可能是 在生活方式和健康状况的许多不同措施中， 通常与可能具有多种措施组合的戒酒者相比， 是相当不温和的，或者至少，非常不同。 因此，在本发明中， 而不是衡量基于酒精的健康结果的差异 研究人员经常在中等和中等消费之间进行研究， 例如，他们正在比较生病的前酗酒者和相对健康的人， 适度饮酒者 同样，生病的从不喝酒的人可能被比作 适度饮酒者。 在任何一种情况下， 适度饮酒被其他因素所掩盖， 健康结果与适度饮酒或戒酒无关。 从这个项目的结果将允许一个更有见地的检查的作用 适量饮酒可以预防某些慢性疾病。

APPLICANT'S ABSTRACT: The purposes of the proposed project are to determine if abstainers have a higher prevalence of physical and mental illness compared to light-to-moderate alcohol drinkers and, amongst abstainers, determine if differences exist in regard to prevalence of physical and mental illness. Socio-demographic measures, lifestyle and ethnic/cultural differences will also be examined for abstainers and light-to-moderate alcohol consumers. To this end, a nationally representative data set, the National Longitudinal Alcohol Epidemiologic Survey will be used to: (1) measure alcohol use in terms of frequency quantity and binge drinking, (2) distinguish amongst those abstaining based on differences in health, smoking, ethnicity and socio- demographic measures, (3) determine amongst those abstaining if there are differences in risk of heart disease by type of abstainer; sick never drinkers, healthy never drinkers, former light, moderate, heavy drinkers, abusing drinkers, (4) determine amongst those abstaining if there are differences in risk of depression by type of abstainer, (5) determine if abstainers have higher levels of depression/mood problems than those not abstaining when controlling for socio-demographic variables, ethnicity and physical illness, and (6) determine if abstainers have higher levels of heart disease, compared to those not abstaining. Information from these activities will serve two related purposes: First, to increase our understanding of the correlates of abstention, particularly differences across age, gender and ethnicity. Second, to increase our ability to classify abstainers into etiologically meaningful categories relevant to moderate alcohol and health. Often moderate drinkers, who may also be moderate in many different measures of lifestyle and health status, are typically compared to abstainers who may have combinations of measures that are considerably less moderate, or at the least, very different. Thus, instead of measuring differences in health outcomes based on alcohol consumption between moderate and abstention categories, researchers frequently are comparing, for example, sick former heavy drinkers with relatively healthy moderate drinkers. Similarly, sick never drinkers might be compared to moderate alcohol drinkers. In either case, the possible beneficial effect of moderate alcohol use is obscured by other factors that may be influencing health outcomes independently from moderate alcohol use or abstention. Results from this project will allow a more insightful examination of the role of moderate alcohol in protecting against certain chronic diseases.