Synthetic Electrochemistry: Carboxylic Acid Derivatives as Radical Precursors

自由基化学在有机合成中的应用非常广泛，但典型的自由基反应也存在问题：自由基前体的制备可能需要额外的合成步骤，而反应本身经常需要高温并使用剧毒的锡试剂。在这个项目中，我们将使用电化学技术来开发绿色自由基合成程序，在室温下进行，使用容易获得和廉价的前体。

The use of radical chemistry in organic synthesis is widespread, yet typical radical reactions are not without their problems: preparation of radical precursors can require additional synthetic steps, while the reactions themselves frequently need elevated temperatures and utilize highly toxic tin reagents. In this project, we will use electrochemical techniques to develop green synthetic radical procedures which proceed at room temperature and use readily available and cheap precursors.