INSTITUTIONAL NATIONAL RESEARCH SERVICE AWARD (T32)

描述 （申请人描述）：爱荷华州大学肿瘤学 研究培训计划旨在支持博士后研究 在一个有指导的环境中为杰出的医学博士提供培训。博士学位。希望 成为癌症研究人员，并获得必要的知识和技能， 进行独立的癌症研究，包括基础实验室和临床 research. 该计划是基于30名经验丰富的教师的专业知识 成员是爱荷华州大学癌症中心的成员。 一般专业领域包括1）癌症免疫治疗，2）细胞 活化和肿瘤生物标志物，3）临床肿瘤学，重点是 泌尿系肿瘤学和骨髓移植，4） 转移，5）自由基和癌症，和6）癌症流行病学。的 大多数候选人都有医学博士学位学位，并已完成两个 他们的住院医师培训和他们的临床密集部分， 专科肿瘤学培训少数受训人员将拥有博士学位。和 承诺致力于从事癌症研究。期间 在支持方面，至少75%的参与者时间将用于 癌症研究培训。该计划将设在大学内， 爱荷华州癌症中心。三年的课程将分为最初的 一年（核心年）和两年直接用于研究培训 （研究年份）。 在核心年度的前六个月， 将参加临床研究和基础研究轮换，以获得 熟悉 在各个方面都是最先进的 基础肿瘤学 r e s。 此外，他们还将参加癌症生物学课程， 流行病学/生物统计学、信息学和医学伦理学。他们还将 开始一段密集的癌症研究培训的指导下， 一位经验丰富的癌症调查员指导研究将在 多年的研究。学员的进度将由一名 个人指导委员会和计划咨询委员会和计划 导演在该计划完成后，预计学员将有 深入了解癌症研究的各个方面， 能够在学术环境中作为独立的癌症研究人员。

DESCRIPTION (Applicant's Description): The University of Iowa Oncology Research Training Program is designed to support postdoctoral research training in a mentored environment for outstanding M.D.'s and Ph.D.'s who wish to become cancer researchers and acquire the knowledge and skills necessary to perform independent cancer research including basic laboratory and clinical research. The program is based on the expertise of 30 experienced faculty members who are members of the Cancer Center at the University of Iowa. General areas of expertise include 1) Cancer immunotherapy, 2) Cellular activation and tumor biomarkers, 3) Clinical oncology with an emphasis on urologic oncology and bone marrow transplantation, 4) Molecular mechanisms of metastasis, 5) Free radicals and cancer, and 6) Cancer epidemiology. The majority of candidates will have the M.D. degree, and have completed both their residency training and the clinically intensive portion of their subspecialty oncology training. A minority of trainees will have a Ph.D. and a stated commitment to pursuing a career in cancer research. During the period of support, at least 75 percent of participants' time will be devoted to cancer research training. The program will be based within The University of Iowa Cancer Center. The three-year curriculum will be divided into the initial year (core year) and two years dedicated directly to research training (research years). During the first six months of the core year, all trainees will participate in clinical research and basic research rotations to gain a familiarity with various aspects of state-of-the-art basic oncologic r e s earch. In addition, they will attend classes in cancer biology, epidemiology/biostatistics, informatics, and medical ethics. They will also begin an intensive period of cancer research training under the mentorship of an experienced cancer investigator. Mentored research will be continued during the research years. Progress of trainees will be monitored continuously by a personal mentoring committee and by the program advisory committee and Program Director. On completion of the program, it is expected that trainees will have a thorough understanding of the various aspects of cancer research, and be able to function as independent cancer researchers in an academic setting.