TRAINGING PROGRAM IN CANCER BIOLOGY

描述（申请人的描述）：癌症生物学培训计划 是 一个为博士前和博士后培训生设计的项目， 专门研究生物和化学问题的调查人员 在他们的研究生涯中与癌症问题有关。我们的计划将 让学员清楚地了解 人类癌症的基本问题和临床问题。该计划是锚定在 维克森林大学癌症中心癌症生物学系; 所有教师要么是主要的癌症生物学系成员，或 交叉任命到癌症生物学 交叉任命的人来自 化学、生物化学、病理学、放射肿瘤学和 血液学/肿瘤学。 受训人员将包括博士预科博士。 候选人， 博士后和医学博士希望能在临床训练之外 接受过癌症研究方面的培训所有的博士前培训生将是候选人 博士学位 癌症生物学学位，威克大学的学位候选人计划 森林大学于1997年秋季学期开学。博士前和博士后 培训将结合联合收割机研究，研讨会/座谈会的参与，加上 由系教师讲授的教学课程，涵盖DNA损伤和 修复，癌细胞生物学，信号转导，细胞周期调控，肿瘤 免疫学、基因治疗及临床和流行病学问题概述 在人类癌症中。研究将由系主任指导; 具体任务将由计划执行委员会在 与监督委员会协商。培训计划的主要特点 包括一个广泛指导和评估过程， 积极的研究项目，结合临床和基础科学。本次培训 该计划将以三种方式实现国家癌症研究所的目标： (1)它将培养出有能力专注于癌症问题的研究人员， （2）教育内容涵盖化学领域， 生物界面;（3）它将强调基础科学之间的联系 和人类癌症的临床问题。

DESCRIPTION (Applicant's Description): The Training Program in Cancer Biology is a program for pre- and postdoctoral trainees designed to produce investigators who will focus on biological and chemical issues specifically related to the cancer problem during their research careers. Our program will impart to trainees a clear understanding of the relationships between the basic problems and clinical issue of human cancer. The Program is anchored in the Department of Cancer Biology of the Wake Forest University Cancer Center; all faculty are either primary Cancer Biology Department members, or are cross-appointed to Cancer Biology. The cross appointees come from the Departments of Chemistry, Biochemistry, Pathology, Radiation oncology, and Hematology/Oncology. Trainees will include predoctoral Ph.D. candidates, postdoctoral Ph.D.'s and M.D.'s desiring to supplement their clinical training with training in cancer research. All predoctoral trainees will be candidates for a Ph.D. degree in Cancer Biology, a degree candidacy program of Wake Forest University begun in the fall semester, 1997. Pre- and postdoctoral traineeships will combine research, seminar/symposia participation, plus didactic coursework taught by Department faculty covering DNA damage and repair, cancer cell biology, signal transduction, cell cycle control, tumor immunology, gene therapy and an overview of clinical and epidemiologic issues in human cancer. Research will supervised by Departmental faculty preceptors; specific assignments will be made by the Program executive committee in consultation with an oversight board. Key features of the Training Program include an extensive mentoring and evaluation process and a faculty with active research programs that mesh clinical and basic science. This training program will address the goals of the National Cancer Institute in three ways: (1) it will produce investigators equipped to focus on the cancer problem in their research careers; (2) it will provide education spanning the chemical- biological interface; (3) it will emphasize the linkage between basic science and the clinical problems of human cancer.