Postpartum Smoking and Infant ETS Reduction Trial

描述(由申请人提供)：本建议书的目的是建造 有指导的临床研究培训经验，以培养独立的 癌症控制研究的专业发展。此应用程序是 由宾夕法尼亚大学癌症中心提交，该中心 提供了一个与Caryn Lerman博士合作的绝佳机会， 跨学科烟草使用研究中心(TTURC)和我的联合赞助商， 查尔斯·奥布莱恩博士和J·桑福德·施瓦茨博士。良好的职业发展 癌症控制研究需要广泛接触研究方法和 强化研究培训，以使有意义的、独立的 对这一领域的贡献。因此，本次K07职业发展奖 应用程序旨在实现烟草控制领域的这些目标和 妇幼保健。职业发展计划的总体计划 包括：(A)扩大与癌症/烟草有关领域的工作知识 控制研究；(B)行为科学应用中的提炼技能 癌症/烟草控制；(C)增加对产妇保健问题的了解 与癌症/烟草控制有关；(D)扩大对 烟草成瘾的生物行为机制；(E)提高 设计、实施和分析癌症/烟草控制干预措施； 和(F)学习传播研究成果以产生影响的有效方法 公共卫生实践。具体地说，该研究项目旨在 开发低成本的初级保健干预措施，以减少儿童的环境- 精神烟草烟雾暴露和母亲吸烟率以以下儿童为目标 为有0-2岁孩子的母亲提供服务。这一干预措施的有效性 将通过将其与标准护理对照组干预进行比较来进行测试 采用两组重复测量的随机设计。这项干预将 模仿更密集的、以家庭为基础的咨询项目 它的可行性已经得到了论证。然而，由于这些干预措施 是劳动密集型和昂贵的，拟议的干预提出了一种 创新、全面、尽管简化了初级保健方法，以 烟草控制领域新出现的问题。这一干预还将设置 为最终测试治疗和预防的R01奠定基础 这一干预措施对其他人群(例如青少年吸烟者)的效果 和他们年轻的、不吸烟的兄弟姐妹)。

DESCRIPTION (provided by applicant): The purpose of this proposal is to build a mentored, clinical research training experience to foster independent professional development in cancer control research. This application is being submitted from the University of Pennsylvania Cancer Center, which provides a setting with excellent opportunities to work with Dr. Caryn Lerman, the Transdisciplinary Tobacco Use Research Center (TTURC), and my co-sponsors, Drs. Charles O'Brien and J. Sanford Schwartz. Sound career development in cancer control research requires broad exposure to research methodologies and intensive research training in order to make significant, independent contributions to this field. Therefore, this K07 Career Development Award application seeks to achieve these goals in the area of tobacco control and maternal and child health. General plans for the career development program include: (a) expanding working knowledge of areas relevant to cancer/tobacco control research; (b) refining skills in the application of behavioral science to cancer/tobacco control; (c) increasing knowledge of maternal health issues related to cancer/tobacco control; (d) expanding understanding of the biobehavioral mechanisms of tobacco addiction; (e) improving skills in designing, implementing, and analyzing cancer/tobacco control interventions; and (f) learning effective ways to disseminate research findings to impact upon public health practices. Specifically, the research project aims to develop a low-cost, primary-care intervention to reduce children's Environ- mental Tobacco Smoke exposure and maternal smoking rates targeting under- served mothers with children ages 0-2. The effectiveness of this intervention will be tested by comparing it with a standard care control-group intervention using a two-group, repeated measures randomized design. The intervention will be modeled after more intensive, home-based counseling programs, the feasibility of which has been demonstrated. However, as these interventions were labor intensive and costly, the proposed intervention presents an innovative, comprehensive, albeit streamlined primary-care approach to an emerging issue in the tobacco control field. This intervention will also set the groundwork for an eventual R01 that will test the treatment and prevention efficacy of this intervention on other populations (e.g., adolescent smokers and their younger, nonsmoking siblings).