MBRS SCORE at The University of Texas-Pan American

描述（由申请人提供）：德克萨斯大学泛美分校MBRS-SCORE项目的目标是帮助支持我们校园内卓越生物医学科学研究基础设施的发展。目前的项目旨在通过要求研究基金来支持一些最有才华的教师、员工和学生研究人员的研究工作，从而促进这一进程。这个SCORE应用程序得到了子项目提交数量的支持，从1997年到2001年增加了一倍多。在这个提案中，20名教员将参与17个子项目。这些研究人员代表了创纪录数量的院系参与，汇集了来自生物学、化学、社会学、心理学、护理学、营养学、经济学、人类学和工程学的教员。因此，UTPA的SCORE方案将从广泛和多样化的角度解决健康问题。子项目的主题范围从可能提供抗癌保护的肉豆蔻素抗癌作用机制的基础研究、通过有机金属剂合成药物的新方法、化学混合物的代谢毒性，到影响卫生政策的广泛社会行为问题，以及影响健康结果并代表治疗和预防关键途径的社会和生物因素的相互作用。

DESCRIPTION (provided by applicant): The goal of the MBRS-SCORE Program at The University of Texas Pan American is to help support the development of a research infrastructure of excellence in the biomedical sciences on our campus. The current program is designed to facilitate this process by requesting research funds to support the research endeavors of some of its most talented faculty, staff and student researchers. This SCORE application is bolstered by the number of subproject submissions, which more than doubled between 1997 and 2001. In this proposal twenty faculty members will be involved in seventeen subprojects. These investigators represent a record number of departmental involvement bringing together faculty from the departments of biology, chemistry, sociology, psychology, nursing, dietetics, economics, anthropology and engineering. Thus the SCORE program at UTPA will be addressing health problems from a broad and diverse perspective. Subprojects range in topic from basic research in the mechanism of anticarcinogenic effects of myristicin that may provide protection against cancer, novel synthesis of medicinal drugs via organometallic agents, toxicity of metabolism of chemical mixtures to broad social-behavioral concerns affecting health policy and the interaction of social and biological factors that influence health outcomes and represent critical avenues for treatment and prevention. Moreover, a primary objective of the proposed SCORE application is to increase the number of underrepresented groups participating in the biomedical sciences. This will be accomplished by expanding the opportunities for underrepresented researchers and students, mostly Hispanic (Latino), and by fostering an engaging research culture on campus that will promote quality graduate education in South Texas. Our geographical location and our high Hispanic enrollment with many of our students of a migrant-farmwork background provide us with all the necessary requisites to sucessfully fulIfill this endeavor.