Xenobiotic Receptors in toxicology and Carcinogenesis

描述（由申请人提供） 在过去的几年里，人们在发现和理解被外来化合物激活的受体方面取得了迅速的进展。 因此，科学、政府和工业界对这些受体的兴趣急剧增加。 目前对这些受体的研究涵盖了广泛的科学学科。 因此，我们的目标是汇集来自工业，政府和学术界，博士后研究员和学生的研究人员，探索外源性受体作为毒物，致癌物，内源性化合物和药物的靶点的作用。 会议将利用既定的年度专题讨论会举行，题为“宾夕法尼亚州立大学分子生物学夏季专题讨论会“，本次会议的标题是“毒理学和致癌作用中的外源性受体”。“这次会议将重点关注受体途径之间可能的串扰，以及外源性物质如何激活一个以上的受体。 会议的结构是为了吸引毒理学，癌症研究和内分泌学方面的个人，目的是增加不同学科科学家之间的互动，这些科学家通常不会参加同一次会议。 另一个目标是通过提供部分旅行支持和保持低注册费，使学生和博士后研究人员能够很容易地参加这次会议。 已建立了一个详细的网站：http：//www. bmb。psu。edu/symposium/.

DESCRIPTION (provided by applicant) The past several years have witnessed rapid advances in the discovery and understanding of receptors that are activated by foreign compounds. As a result, scientific, governmental and industrial interest in these receptors has increased dramatically. Current research on these receptors now encompasses a broad range of scientific disciplines. Thus, our goal is to bring together investigators from industry, government, and academics, post-doctoral fellows, and students to explore the role of xenobiotic receptors as targets for toxicants, carcinogens, endogenous compounds and drugs. The meeting will be held utilizing the established annual symposium entitled "Penn State 's Summer Symposium in Molecular Biology " with the title for this meeting being "Xenobiotic Receptors in Toxicology and Carcinogenesis." This meeting will focus on possible cross talk between receptor pathways as well as how xenobiotics may activate more than one receptor. The meeting has been structured to appeal to individuals in toxicology, cancer research, and endocrinology, with the goal of increasing interactions between scientist in different disciplines that do not routinely attend the same meeting. Another goal is to make this meeting highly accessible to students and post-doctoral fellows by providing partial support for travel and keeping the registration fee low. A detailed web site has been established: http://www. bmb. psu. edu/symposium/.