Gordon Conference on Environmental Endocrine Disruptors

第三届戈登环境内分泌干扰物研究会议将于2002年7月14日至19日在华盛顿哥伦比亚特区举行。马萨诸塞州南哈德利的霍利奥克学院。 这次会议，比任何其他会议，将汇集一个不同的科学家群体在这个跨学科的主题互动。 人类和野生动物暴露于大量广泛使用的已知或怀疑具有雌激素或抗雄激素活性或干扰甲状腺激素作用的环境化学品。野生动物研究强烈表明，这些环境内分泌干扰物（EEDs）以多种方式严重影响种群（内分泌和生殖系统功能失调，行为改变，畸形，从而减少生殖和种群数量）。 EEDs还被认为会导致人类生殖道畸形以及睾丸癌和乳腺癌。 美国、日本政府和欧盟正在收集信息，资助大型研究工作，并在某些情况下颁布监管EED的法律。 在美国，《安全饮用水法》和《食品质量保护法》的修正案要求对水和食品中发现的化学物质进行EED活性测试。 环境内分泌干扰物戈登会议的目标是：1）在所有复杂程度上呈现最先进的研究（从分子到群体），2）强调了解内分泌干扰的机械方法，3）致力于整合来自这些不同调查领域和生物复杂性水平的数据，4）确定知识差距和新的探索领域，5）加强科学家之间的有效沟通，促进新的合作研究努力。 受邀演讲者的名单包括知名领导人以及最近报告了令人兴奋的发现的年轻科学家。除了NIEHS，本次会议的跨学科性质是其他几个研究所的潜在兴趣，包括NICHD（内分泌干扰物对男性和女性生殖道和乳腺的发育影响），NIDDK（类固醇激素受体，甲状腺功能，生殖内分泌学）和NCI（内分泌干扰物作为致癌物）。

The third Gordon Research Conference on Environmental Endocrine Disruptors will be held on July 14-19, 2002, at Mt. Holyoke College in South Hadley, Massachusetts. This conference, more than any other, will bring together a diverse group of scientists to interact in this interdisciplinary subject. Humans and wildlife are exposed to a large number of widely used environmental chemicals known or suspected to have either estrogenic or antiandrogenic activities, or to interfere with thyroid hormone action. Wildlife studies strongly suggest that populations are severely affected by these environmental endocrine disruptors (EEDs) in a number of ways (dysfunctional endocrine and reproductive systems, altered behavior, malformations, and thus reduced reproduction and population numbers). EEDs are also thought to cause malformations of the human genital tract as well as testicular and breast cancers. The US and Japanese governments and the European Union are gathering information, funding large research efforts, and in some cases, enacting laws regulating EEDs. In the US, amendments to the Safe Drinking Water Act and the Food Quality Protection Act mandate testing chemicals found in water and food for EED activity. The objectives of the Environmental Endocrine Disruptors Gordon Conference will be to: 1) present state-of-the-art research at all levels of complexity (molecular to population), 2) emphasize mechanistic approaches to the understanding of endocrine disruption, 3) work at integrating data emerging from these different fields of inquiry and levels of biological complexity, 4) identify gaps in knowledge and emerging areas of inquiry for exploration, and 5) enhance effective communication between scientists and foster new collaborative research efforts. The roster of invited speakers includes established leaders as well as young scientists who have recently reported exciting findings. In addition to the NIEHS, the interdisciplinary nature of this conference is of potential interest to several other institutes including the NICHD (developmental effects of endocrine disruptors on the male and female genital tract and mammary gland), the NIDDK (steroid hormone receptors, thyroid function, reproductive endocrinology) and the NCI (endocrine disruptors as carcinogens).