Xth Int'l Symposium on Human Chlamydial Infection

要求为第十届人类衣原体感染国际研讨会提供财政支持。沙眼衣原体感染是性传播疾病的最常见原因，往往导致妇女和新生儿出现严重病理。在所有报告给疾病预防控制中心的法定疾病中，沙眼原体是美国报告的最普遍的感染。它还可能增加感染艾滋病毒的风险。这些微生物也是沙眼的病因，沙眼是世界上可预防失明的主要原因。肺炎梭菌被认为是一种非常常见的呼吸道病原体，最近肺炎梭菌与慢性呼吸道疾病和冠状动脉疾病的关联显著增加了对这些感染的了解。分子诊断技术的进步促进了衣原体疾病临床谱的扩大。在阐明衣原体生物与其专性哺乳动物细胞之间复杂的相互作用以及免疫和发病机制的分子机制方面取得了令人兴奋的进展。此外，从最近的沙眼衣原体和肺炎衣原体基因组测序中推断出的信息正在迅速为基本衣原体生物学提供新的见解。这次会议是该领域研究人员交流最高质量研究信息和比较不同国家成果的最重要的聚会。鉴于最近衣原体研究的爆炸式增长，将于2002年6月举行的第x届人类衣原体感染国际研讨会是及时的，因为该会议传统上每四年举行一次。因此，它是有利的，可以预期它将为制定新千年衣原体研究议程提供独特的推动力。

Financial support is requested for the Xth International Symposium on Human Chlamydial Infection. Chlamydia trachomatis infections are the most common cause of sexually transmitted diseases often resulting in severe pathology in women and newborns. Of all notifiable diseases reported to the CDC, C. trachomatis is the most prevalent reported infection in the United States. It may also increase the risk of HIV infection. These organisms are also the cause of trachoma, the leading cause of preventable blindness in the world. C. pneumoniae is recognized as a very common respiratory pathogen and the recent association of C. pneumoniae with chronic respiratory diseases and coronary artery diseases significantly increases the need for understanding these infections. Characterization of the expanded clinical spectrum of chlamydial diseases has been facilitated by advances in molecular techniques for diagnosis. This has been complemented by exciting advances in elucidating the sophisticated interplay between chlamydial organisms and their obligate mammalian cells and the molecular mechanisms of immunity and pathogenesis. Additionally, the information inferred from the recent sequencing of the C. trachomatis and the C. pneumoniae genomes is rapidly providing new insights into fundamental chlamydial biology. This meeting represents the most important gathering for researchers in the field to exchange the highest quality research information and comparison of results among different countries. Given the recent explosion of research on chlamydiae, the Xth International Symposium on Human Chlamydial Infection to be held in June 2002 is timely as this meeting is traditionally held only every four years. It is thus propitious and can be expected to uniquely provide the impetus for setting the research agenda on the chlamydiae for the new millennium.