Antidepressant and antipsychotic drug use in people with diabetes

简而言之，该项目的目标是确定糖尿病患者使用抗抑郁药和抗精神病药物的频率，并调查这是否与血糖控制、血压和体重指数以及血管疾病和糖尿病特异性并发症有关。我还将研究抗抑郁药和抗精神病药的综合作用。更具体地说，我将调查这些关联是否因药物类别或组合而异。这将有助于为后续项目提供信息，这些项目旨在确定哪些患者可能面临某些药物不良反应的最大风险，从而为量身定制的药物处方实践提供信息，并最终提供个性化的患者治疗。用于实现这些目标的数据集将包括苏格兰护理信息-糖尿病数据集和南伦敦和莫兹利NHS基金会信托病例登记册。

In brief, the goals of this project are to identify the frequency of antidepressant and antipsychotic drug use among people with diabetes, and to investigate whether this is associated with glycemic control, blood pressure and body mass index, as well as vascular disease and diabetes specific complications. I will also examine the impact of antidepressant and antipsychotic polypharmacy.More specifically, I will investigate whether these associations differ by drug class or combination. This will help to inform subsequent projects aimed at identifying patients who might be at greatest risk of adverse effects from certain drugs, thus informing tailored drug prescription practices and ultimately providing personalised patient treatment. Datasets utilised to fulfil these goals will include the Scottish Care Information-Diabetes dataset and the South London and Maudsley NHS Foundation Trust case register.