High-Throughput Synthesis, Screening and Optimisation of Fe Catalysts in Industrially-Relevant Transformations

该项目将利用一个独特的流动平台，作为EPSRC拨款的一部分开发，用于高通量合成，筛选和优化工业相关转化中的铁催化剂，铃木耦合和Buchwald/Ullmann aminations是本研究的重点。快速生成催化剂的能力（使用已建立的电化学方法），直接流入催化反应器，再加上在线分析和自动化优化，将提供一种全面的方法来分析催化剂活性，从而导致铁催化的重大进展。

This project will exploit a unique flow platform, developed as part of an EPSRC grant, for high-throughput synthesis, screening and optimisation of Fe catalysts in industrially relevant transformations, with Suzuki couplings and Buchwald/Ullmann aminations being a focus in this research. The ability to rapidly generate catalysts (using established electrochemical methods) with direct flow into a catalytic reactor, coupled with inline analysis and automated optimisation, will provide a holistic approach to profiling of catalyst activity leading to significant advances in Fe catalysis.