Intravitreal Corticosteroid for Macular Edema Study

描述（由申请人提供）：威斯康星州大学眼底照片阅读中心（UW FPRC）拟作为玻璃体内皮质类固醇治疗黄斑水肿研究的照片阅读中心。为此，我们建议： 1.应用当前的程序记录和分级黄斑水肿。我们可以提供黄斑水肿成像（彩色立体眼底照片，荧光素血管造影和光学相干断层扫描）的协议，并在定向，认证和向临床摄影师提供反馈方面经验丰富。通过扩展早期治疗糖尿病视网膜病变研究分类，我们有了根据彩色照片和荧光素血管造影片对黄斑水肿进行评估/分级的方案。我们正在制定一项评估OCT扫描的方案。 2.协助研究主席和研究者1）开展临床试验（例如，及时审查照片和血管造影片的合格性），2）分析结果数据和3）准备出版手稿。 UW FPRC首席研究员和工作人员在参与合作方面经验丰富， 多中心临床试验，并致力于研究糖尿病黄斑水肿和视网膜静脉阻塞的新疗法。

DESCRIPTION (provided by applicant): The University of Wisconsin Fundus Photograph Reading Center (UW FPRC) proposes to serve as photograph reading center for the Intravitreal Corticosteroid for Macular Edema study. To accomplish this, we propose to: 1. Apply current procedures for documenting and grading macular edema. We can provide protocols for macular edema imaging {color stereoscopic fundus photographs, fluorescein angiograms, and optical coherence tomograms), and are experienced at orienting, certifying, and giving feedback to clinic photographers. By extending the Early Treatment Diabetic Retinopathy Study classification, we have protocols for evaluation/grading of macular edema from color photographs and fluorescein angiograms. We are developing a protocol for assessment of OCT scans. 2. Assist the study chair and study investigators in 1) the conduct of the clinical trial (for example, timely review of photographs and angiograms for eligibility), 2) the analysis of the resultant data and 3) the preparation of manuscripts for publication. The UW FPRC principal investigator and staff are experienced at participation in collaborative multi-center clinical trials and are strongly committed to the study of new treatments for macular edema due to diabetes mellitus and retinal vein occlusion.