Cellular/MolecularBasis of Development:Research Center

描述（由申请人提供）： 通过RCMI倡议，CCNY创建了CSCMBD。 该中心建立在RCMI支持领域的学院现有优势基础上，通过增加新的研究活跃的教师来丰富。 现在有21名研究人员参与该中心，分为三个科学领域：第一区域组-生物分子结构和功能;第二区域组-基因表达和调控;第十一区域组-神经生物学。 除了主要的科学领域，该中心的教师的独特技能被编组发展免疫学小组（IS）。 主要设备的采购和中央设施的建立进一步加强了中心内的活动。 今后，保持竞争优势的要求将发生变化。 这些变化要求重新关注研究中心的结构。 目前在全国领先的一个研究领域是免疫学。 由于CCNY以前的一些RCMI雇员在这一领域有专业知识，CCNY的研究中心已经定位自己很容易进入这一研究领域。 将提出计划，聘请一名科学家，以加强这一新的信息系统在第2区。 此应用程序的主要重点是聘请免疫学家，并为新员工提供启动资金。 为了显示其对RCMI计划的支持，CCNY将雇用RCMI的新成员。 在此要求提供资金，以供开办之用。 还要求为体制建设现有三个成员的试点项目提供资金。 Mark Pezzano博士准备了一个试点项目，而琳达斯帕茨博士和保罗戈特利布博士是另一个试点项目提案的共同PI。 行政预算中要求支付薪金，以雇用项目办公室的项目助理。 该申请还要求提供资金，以更新一个核心设施中使用的过时设备的技术，并购买一台流式细胞仪分析仪。

DESCRIPTION (provided by applicant): Through the RCMI initiative, CCNY created the CSCMBD. The Center, built on the existing strengths of the College in the RCMI-supported areas, was enriched by the addition of new research-active faculty members. There are now 21 researchers participating in the Center, grouped in three scientific areas: Area Group I - Biomolecular Structure and Function; Area Group II - Gene Expression and Regulation; and Area Group 11 - Neurobiology. In addition to the main scientific areas, the unique skills of the Center's faculty were marshaled to develop an Immunology Subgroup (IS). Major equipment purchases and the creation of central facilities further enhanced the activity within the Center. In the future, the demands for the maintenance of a competitive edge will change. Such changes have required a refocusing of attention to the structure of the Research Center. One area of research that is currently leading the national scene is immunology. Because a number of previous CCNY's RCMI hires have had expertise in this field, the Research Center at CCNY has positioned itself to easily move into this area of research. Plans will be presented to hire a scientist to enhance this new IS within Area 2. The major focus of this application is to hire an immunologist and to provide start-up funds for the new hire. To show its support for the RCMI program, CCNY will hire the new addition to the RCMI. Funds are requested here to provide their start-up. Funds are also requested for pilot projects for three of the existing members of the IS. Dr. Mark Pezzano has prepared one pilot project, while Drs. Linda Spatz and Paul Gottlieb are co-PIs on another pilot project proposal. Salaries are requested in the administrative budget to hire a Project Associate for the Program Office. This application also includes a request for funds to update technology of outdated equipment used in one of the core facilities and to purchase a FACS analyzer.