Identification and validation of candidate genes for resistance to soil-borne Rhizoctonia solani in Brassica crop species

生长素几乎协调了植物生长和发育的各个方面，因此是改善粮食安全的关键目标。然而，尽管它很重要，但我们对植物整体生长素分布的调节以及这如何影响植物结构缺乏基本的了解。该项目将使用建模方法来了解生长素经济如何影响拟南芥幼苗生长。生长素是在植物的茎尖和根尖合成的，可以长距离传播以调节远离其合成点的生长；然而，生长素合成和长距离运输对控制生长表型的相对重要性尚不清楚；本项目将研究长途运输控制整体生长素经济的假设，以确定幼苗结构。为了分析长途运输对幼苗结构的影响，本项目将在已建立的SimRoot根系建模框架的基础上，开发模拟幼苗生长素动态和生长的计算模型。该模型将形成一个独特的平台，以精确地研究生物尺度的生长素动力学如何控制幼苗生长。

Auxin orchestrates nearly every aspect of plant growth and development, and thus represents a crucial target in improving food security. However, despite its importance, we lack fundamental knowledge of the regulation of the plant's overall auxin distribution, and how this impacts plant architecture. This project will use a modelling approach to understand how the auxin economy impacts Arabidopsis seedling growth. Auxin is synthesised in the plant's shoot and root tips, and can travel long distances to regulate growth far from its synthesis site; however, the relative importance of auxin synthesis and long-distance transport for controlling growth phenotypes is unknown; this project will investigate the hypothesis that long-distance transport controls the overall auxin economy to determine seedling architecture. To analyse how long-distance transport impacts seedling architecture, this project will develop computational models to simulate seedling auxin dynamics and growth, building on the established SimRoot root-system modelling framework. The model will form a unique platform to investigate precisely how organism-scale auxin dynamics control seedling growth.