Prostate cancer in Blacks: Role of poverty and diet

候选人的长期职业目标是成为癌症预防和控制的独立研究者，重点研究癌症发病率和死亡率的种族和民族差异。 少数群体承受着不平等的癌症负担，候选人建议开发独特和创新的方法来帮助理解这些差异。 K 07将在两个领域提供新的和增强的知识和技能的发展，这两个领域对候选人未来的研究工作至关重要，旨在帮助减少癌症健康差异：1）空间流行病学，包括使用地理信息系统; 2）癌症预防和控制，包括健康行为（特别是关于饮食和体育活动）。 拟议的培训计划包括：1）课程工作; 2）赞助商和合作者的定期指导; 3）参加研讨会和国家会议; 4）专家辅导; 5）指导研究。 K 07教学经验将应用于指导研究项目中。 项目具体目标：1）开发一个地理信息系统，绘制美国东南部前列腺癌发病率; 2）开发空间回归模型，旨在解释贫困，收入，城市/农村居住和种族与前列腺癌发病率地理模式的可能联系; 3）在弗吉尼亚州选定的农村和城市地点，对非裔美国人和白人的膳食脂肪摄入量进行电话调查;以及4）调查这些地区的膳食脂肪摄入量与前列腺癌发病率之间是否存在任何相关性。 K 07项目的研究结果将用于帮助非洲裔美国人社区制定文化上适当的干预措施，以减少膳食脂肪摄入量和增加体育活动。

DESCRIPTION (provided by applicant): The Candidate's long-term career goal is to become an independent investigator in cancer prevention and control, with a focus on studying racial and ethnic disparities in cancer morbidity and mortality. Minority populations bear an unequal cancer burden, and the Candidate proposes to develop unique and innovative methodologies to help understand these disparities. The K07 will provide for the development of new and enhanced knowledge and skills in two areas essential to the Candidate's future research efforts aimed at helping to reduce cancer health disparities: 1) spatial epidemiology, including use of geographic information systems; and, 2) cancer prevention and control, including health behavior (especially regarding diet and physical activity). The proposed training plan includes 1) course work; 2) regular mentoring from Sponsors and Collaborators; 3) participation in seminars and national conferences; 4) tutorials by experts; and, 5) mentored research. K07 didactic experiences will be applied in a mentored research project. Specific Aims of Project: 1) develop a geographic information system that maps prostate cancer incidence in the southeastern United States; 2) develop spatial regression models aimed at explaining the possible association of poverty, income, urban/rural residence, and race to the geographic patterning of prostate cancer incidence; 3) conduct a telephone survey of dietary fat intake among African Americans and whites in selected rural and urban sites in Virginia; and 4) investigate whether any correlation exists between dietary fat intake in these areas and the incidence of prostate cancer. K07 project findings will be used to help develop culturally appropriate interventions in African-American communities to decrease dietary fat intake and increase physical activity.