CORE--INTERNATIONAL RESEARCH FACILITY

全世界每天有1200多名儿童死于艾滋病毒感染及其并发症。据报道，病例数量在几个地理区域大幅增加，包括东欧、东南亚以及东亚和太平洋地区。在一次独特的合作中，贝勒医学院与罗马尼亚的几个医疗和科学机构合作，建立了一个儿童艾滋病毒保健专业教育和临床研究方案。拟议的国际研究核心旨在通过在罗马尼亚建立实验室基础设施来扩大现有方案的范围并扩大和加强其活动，以促进艾滋病毒临床和基础研究项目的合作。国际研究中心的具体目标如下：(1)作为贝勒医学院科学家与罗马尼亚临床医生和科学家之间的联络人，共同开发、实施和执行HW合作研究；(2)提供实验室基础设施支持或标本的采购、加工、储存和运输；以及(3)为补充罗马尼亚根据现有的罗南-美国儿童艾滋病教育和临床研究方案以及计划的艾滋病国际培训和研究方案开展的保健、专业和科学教育活动：n.将在布加勒斯特的斯特凡·S·尼古劳病毒学研究所建立一个设施，用于处理和储存对CFAR研究活动重要的标本。研究所的工作人员将协助确定罗马尼亚的合作者，并将促进1J.S.和罗马尼亚调查人员之间的沟通。该研究所将作为罗马尼亚与美国合作的硬件研究和卫生保健专业教育活动的协调中心。

Worldwide, over 1200 children die each day from HIV infection and its complications. Large increases in case numbers are being reported in several geographic regions, including Eastern Europe, Southeast Asia, and East Asia and the Pacific. In a unique collaboration, Baylor College of Medicine, in cooperation with several Romanian medical and scientific institutions, has established a program for pediatric HIV health-care professional education and clinical research. The purposes of the proposed International Research Core are to broaden the scope and expand and enhance the activities of the existing prograrn by establishing laboratory infrastructure in Romania to facilitate collaborative HIV clinical and basic research projects. The specific aims of the International Research Core are as follows: (1) to serve as a liaison between scientists at Baylor College of Medicine and Romanian clinicians and scientists in the development, implementation, and execution of HW collaborative research; (2) to provide laboratory mfrastructure support Ior specimen procurement, processing, storage, and shipping; and (3) to complement Romanian health professional and scientific educational activities conducted under the existing Rornanian-American Pediatric AIDS Education and Clinical Research Program and the planned AIDS International Training and Research Prograi:n. A facility will be established at the Stefan S. Nicolau Institute of Virology in Bucharest for the processing and storage of specimens important for CFAR research activities. Institute staff will assist in the identification of Romanian collaborators and will facilitate communication between1J.S. and Romanian investigators. The Institute will serve as the focal point for collaborative Romanian-U.S. HW research and health-care professional educational activities.