Core--Clinical

临床核心将为两个临床项目提供支持，项目1 （Matthay）和项目2 （Wiener-Kronish）。从本质上讲，这个核心将是一个临床协调中心，配备人员来支持临床研究。该临床中心将为Moffitt-Long医院和旧金山总医院成人和儿科重症监护病房的合格患者筛查和登记提供组织、人员和用品。临床核心还将为患者数据和患者标本的获取和输入、数据分析和临床研究各方面的监测提供支持，以符合良好临床实践和NIHLBI、FDA和UCSF IRB指南。该核心还将提供数据的统计分析，并支持根据需要修改数据库集合。

The Clinical Core will provide support for the two clinical projects, Project 1 (Matthay) and Project 2 (Wiener-Kronish). Essentially, this core will be a clinical coordinating center staffed to support the clinical studies. This clinical core will provide the organization, personnel and supplies for the screening and enrollment of eligible patients in the adult and pediatric intensive care units at Moffitt-Long Hospital and San Francisco General Hospital. The clinical core will also provide the support for acquisition and entry of patient data and patient specimens, data analysis, and monitoring of all aspects of the clinical studies so as to conform with Good Clinical Practice and NIHLBI, FDA, and UCSF IRB guidelines. This core will also provide statistical analysis of the data and the support to modify database collection as needed.