2003 Kern Aspen Lipid Conference: Integrative Mechanisms

描述(由申请人提供)： 本申请旨在为将于2003年8月16日至19日在科罗拉多州阿斯彭举行的2003年克恩·阿斯彭脂肪会议寻求资金。会议的题目是《脂类代谢的综合机制》。这次会议的目标将是为与会者提供机会，了解超越任何一个单一研究领域的广泛脂代谢领域的最新发现。脂类研究与来自各种方法的想法的交叉培养应该对所有人都是有教育意义的，并可能促进新的研究倡议。因此，今年会议选出了三名共同主席，他们都有不同的背景。劳伦斯·鲁德尔博士是董事会成员，是脂蛋白新陈代谢和胆固醇运输方面的专家。小罗伯特·法雷塞博士。是三酰甘油和脂肪酸代谢方面的专家，并开发了许多甘油三酯代谢的动物模型。约阿希姆·赫兹博士是中枢神经系统研究方面的专家，他在中枢神经系统研究领域率先对正常大脑发育和功能所需的几种细胞表面受体进行了鉴定和功能评估。第四次会议将讨论与代谢综合征相关的转录因子和遗传学，这一次会议将由克里斯托弗·格拉斯博士领导。组织这次会议的目的是将脂类研究中不同领域的研究人员聚集在一起，目的是促进对涉及脂类代谢的疾病(包括动脉粥样硬化、糖尿病和肥胖症)的发病机制的进一步了解。虽然一些拟议的主题可能会在其他专门会议上讨论，但我们并不知道有一个单一的会议，其中包括聚集在一起的各种领域的多样性，以在如此广泛的领域交流脂代谢的新进展。这次会议的及时性被视为一种优势。

DESCRIPTION (provided by applicant): This application is to seek funding for the 2003 Kern Aspen Lipid Conference, to be held in Aspen, CO, on August 16-19, 2003. The title of the conference is "Integrative Mechanisms of Lipid Metabolism". The goal of this meeting will be to provide attendees the opportunity to learn about the state-of-the-art findings across broad areas of lipid metabolism that extend beyond any one single research area. Cross fertilization of lipid research with ideas from a variety of approaches should be educational to all, and may promote new research initiatives. Accordingly, three co chairs for this year's meeting were selected, all of whom have different backgrounds. Dr. Lawrence Rudel is a member of the board of directors and is an expert in lipoprotein metabolism and cholesterol transport. Dr. Robert Farese, Jr. is an expert in triacylglycerol and fatty acid metabolism and has developed numerous animal models of acylglyceride metabolism. Dr. Joachim Herz is an expert in studies of the central nervous system, where he has pioneered identification and functional evaluation of several cell surface receptors that are required for normal brain development and function. A fourth session will cover transcription factors and genetics associated with the metabolic syndrome, and this session will be led by Dr. Christopher Glass. The conference is organized to bring together investigators in divergent fields in lipid research with the goal to foster further insights into the pathogenesis of diseases involving lipid metabolism including atherosclerosis, diabetes, and obesity. Although some of the proposed subjects may be covered at other specialized meetings, we are unaware of a single conference, which includes the diversity of the various fields assembled to exchange new advances in lipid metabolism across such a wide ranging arena. The timeliness of this meeting is viewed as a strength.