Basic Mechanisms in Virology

描述(由申请者提供)：该计划的目标是提供高质量的博士后和博士后培训，并为从事病毒学基本机制的研究和教学工作的优秀个人做准备。我们从UAB的30多名病毒学家中挑选了那些研究项目侧重于病毒学基本机制的人，以建立一个由18名研究人员组成的多学科、多部门的小组，他们在病毒的分子和结构生物学方面具有成熟的专业知识和研究兴趣。这些教员目前的研究兴趣包括病毒和病毒组件的结构和组装的调查，RNA和DNA疫苗的遗传和复制，病毒蛋白质的结构与功能关系，以及新型抗病毒药物和疫苗的开发。这项建议中的教职员工所在的实验室设备齐全，资金充足，可用于所有阶段的研究。来自生物化学、微生物学、儿科和医学系的参与教职员工认为，我们拥有良好的环境，可以在现代分子病毒学方面提供出色的博士后和博士后培训。博士前实习生是在他们第一年的学习后从高素质的学生中挑选出来的，这些学生进入了一个名为“细胞和分子生物学(CMB)研究生项目”的多部门项目或一个高度选择性的医学博士/博士项目。对攻读病毒学基本机制课程的博士后和博士后学员的具体要求包括参加病毒学高级课程、期刊俱乐部、每周的病毒学研究研讨会以及参加院系研讨会。学生需要相关领域的其他高级课程，博士后实习生也可以参加。鼓励学员申请个人奖学金和奖项，并指导他们如何撰写研究计划。除了研究活动和课程外，培训计划还包括参加地方、地区和国家科学会议。博士后和博士后实习生的招聘将通过各种招聘方案在国家一级进行，并将鼓励招募少数民族参与者。

DESCRIPTION (provided by applicant): The objective of this program is to provide high quality training at the predoctoral and postdoctoral levels and to prepare outstanding individuals for careers in research and teaching in Basic Mechanisms of Virology. We have selected from among the more than 30 virologists at UAB those whose research programs focus on Basic Mechanisms in Virology to develop a multidisciplinary, multi-departmental, group of eighteen investigators with proven expertise and research interests in molecular and structural biology of viruses. The ongoing research interests of these faculty members include investigations of the structure and assembly of viruses and viral components, the genetics and replication of RNA and DNA vaccines, structure-function relationships in viral proteins, and the development of novel antiviral agents and vaccines. The faculty members in this proposal occupy laboratories that are well equipped and well funded for all phases of research. The participating faculty, from the Departments of Biochemistry, Microbiology, Pediatrics, and Medicine, believe that we have at UAB an excellent environment for providing outstanding predoctoral and postdoctoral training in modern molecular Virology. Predoctoral trainees are selected after their first year of study from the pool of highly qualified students entering a multi-departmental program entitled "the Cellular and Molecular Biology (CMB) Graduate Program" or a highly selective M.D./Ph.D. program. Specific requirements for predoctoral and postdoctoral trainees enrolled on the Basic Mechanisms of Virology Program include participation in advanced level courses in virology, a journal club, the weekly Virology research seminars as well as attendance at Departmental seminars. Additional advanced courses in related fields are required for students and available to postdoctoral trainees. Trainees are encouraged to apply for individual fellowships and awards, and are instructed in how to write research proposals. In addition to research activities and courses, the training program includes participation in local, regional, and national scientific meetings. Recruitment of both predoctoral and postdoctoral trainees will be at the national level through a variety of recruitment programs and will encourage recruitment of minority participants.