Event Recordings of High Risk Infants on Apnea Monitors

描述(由申请人提供)：本项目的目的是继续对协作性家庭婴儿监测评估(CHME)研究进行具体分析，继续进行国家婴儿睡眠姿势(NISP)研究，并作为前一次拨款授予期间开发的CHME和NISP的公共使用数据集的资源。CHINE研究招募了五个大学临床站点的近1100名婴儿。CHIME数据集包括来自90万小时(300 GB)家庭监测记录的原始和分析的生理波形；700个夜间多导睡眠图；2.1万个超过记录阈值的心肺事件；6000个超过常规警报阈值的事件；以及600个超过极端阈值的事件。特别是，对CHIME数据的拟议分析将评估预测极端心肺事件的因素和生理过程，包括早期先兆因素、发育模式以及发病和康复的即时特征。NISP研究始于1992年，是对48个相邻州的8个月以下婴儿的夜间照顾者进行的年度电话调查，以评估婴儿护理做法和AAP关于婴儿睡眠姿势的建议的传播。NISP研究的继续将评估婴儿睡眠实践的趋势和“回归睡眠”建议的传播，以及影响这些趋势的因素。将努力提高少数族裔在已完成呼叫中的比例，同时使用当前的名单样本。此外，调查人员将用旨在阐明少数群体不遵守规定的风险因素的替代方法来补充NISP调查。最后，将建立一个基础设施，以便利公众获取CHINE和NISP数据集。公众查阅服务将包括：(1)维护一个网站，提供关于现有数据以及如何获取这些数据的信息；(2)处理有关数据的查询，并维护一个跟踪请求进展情况的数据库；(3)就便利交付所需的数据，即全部或部分数据库，提供咨询；(4)以光盘格式提供数据，并提供适当的文件，以便使用数据；(5)就超出基线支助范围的数据库的使用提供收费咨询。

DESCRIPTION (provided by applicant): The purpose of this project is to continue specific analyses of the Collaborative Home Infant Monitoring Evaluation (CHIME) Study, to continue to conduct the National Infant Sleep Position (NISP) Study, and to serve as a resource for public use datasets from CHIME and NISP, which were developed during the previous grant award period. The CHIME Study enrolled almost 1,100 infants at five university-based clinical sites. The CHIME dataset includes raw and analyzed physiological waveforms from 900,000 hours (300GB) of home monitoring records; 700 overnight polysomnograms; 21,000 cardiorespiratory events exceeding recording thresholds; 6,000 events exceeding conventional alarm thresholds; and 600 events exceeding extreme thresholds. In particular, the proposed analyses of the CHIME data will assess the factors and physiological processes that predict extreme cardiorespiratory events to include early antecedents, developmental patterns, and immediate characteristics of onset and recovery. The NISP Study, begun in 1992, is an annual telephone survey of nighttime caregivers of infants less than eight months of age in the 48 coterminous states to assess infant care practices and dissemination of the AAP recommendation regarding infant sleep position. Continuation of the NISP Study will evaluate trends in infant sleep practices and dissemination of the "Back to Sleep" recommendation, and the factors that influence these trends. Efforts will be made to increase the proportion of minorities in the completed calls, while using the current list sample. Furthermore, the investigators will complement the NISP survey with alternative methodologies designed to illuminate risk factors for non-compliance in minority groups. Finally, an infrastructure will be put in place to facilitate public access to both the CHIME and NISP datasets. The public access service will include: (1) maintaining a website that provide information on the available data and how to obtain it; (2) processing queries regarding the data and maintaining a database that tracks the progress of the requests; (3) providing consultation on the data needed to facilitate the delivery, i.e., all or part of the database; (4) providing the data in CD ROM format with appropriate documentation for use of the data; (5) and providing fee-for-service consultation on the use of the database beyond the baseline support.