Fusing and damping osseointegrated implants

背景尽管长期伤口护理和感染问题未知，但下肢骨整合（OI）植入物在许多方面都是解决关节窝配合问题的理想方案。然而，仍然存在目前完全没有解决的重大机械问题。长期的机械影响也是未知的。这些机械效应主要与机械失效（骨折、植入物松动或连接器失效）相关，并且可能与疼痛或加速骨关节炎（包括骨痛、关节痛、下背痛）相关，这可能是由于冲击载荷从地板通过刚性假体和刚性OI植入物直接传递到骨骼。目前没有定制的工程解决方案。研究问题：“标准”假体能否与OI植入物一起使用，并为用户舒适度、生理过载保护以及OI植入物失效和骨折提供阻尼和冲击保护？PhD aimsThe PhD的目的是开发一个设计工具箱，以优化膝上截肢者骨整合植入物和外部假体之间固定的复杂约束条件，这些约束条件有时相互冲突。该博士学位的详细目标之一是彻底研究OI植入物和残留骨之间的相互作用，因为大多数机械问题都来自该区域。

BackgroundDespite the unknown long-term wound care and infection issues, osseointegrated (OI) implants for the lower limb are, in many ways, an ideal solution for socket fitting problems. There remain, however, significant mechanical issues that are currently totally unaddressed. The long-term mechanical effects are also not known. These mechanical effects are mainly related to mechanical failure (bone fracture, implant loosening, or connector failure) and, potentially,pain or accelerated osteoarthritis (including bone pain, joint pain, lower back pain) likely due to shock loading transmitted from the floor through therigid prosthesis and rigid OI implant directlyto the bone. There are currently no bespoke engineered solutions. Research ProblemCan 'standard' prostheses be used with OI implants and provide damping and shock protection for user comfort, physiological overload protection, and OI implant failure and bone fracture?PhD aimsThe aim of the PhD is to develop a design toolbox to optimise the complex set of, sometimes conflicting, constraints on the fixation between an osseointegrated implant and the external prosthesis for an above knee amputee. One of the detailed objectives of this PhD is to thoroughly investigate the interaction between the OI implant and the residual bone as most mechanical issues arise from this area.