Dental Composite with Reduced Polymerization Stress

描述（由申请人提供）：牙科复合修复材料在放置过程中会发生收缩。当它们在受限环境中光固化时，它们所经历的收缩在与周围牙齿结构的粘结界面处产生应力。通常，这种应力高到足以破坏粘合界面，造成间隙，导致边缘染色，敏感性和复发性衰退。本项目将探索一种替代类型的光引发剂，可以显着降低收缩应力。新化合物将定制合成，其引发聚合的能力与典型的光引发剂相当，将使用FTIR分析在模型复合材料中进行验证。将测量模型复合物的聚合应力并与含有典型光引发剂的复合物进行比较。将含有新型引发剂的复合材料的体外耐磨性和断裂韧性与含有典型引发剂的复合材料进行比较，以确保其临床可行性。将在新型复合材料的离体人磨牙中模拟V类牙列中的微渗漏，以证明其与对照复合材料相比的上级边缘密封。一种产生低聚合应力的复合材料将缓解牙科中长期存在的问题，并可能应用于汽车和电子制造等其他行业。

DESCRIPTION (provided by applicant): Dental composite restorative materials undergo shrinkage during their placement. When they are light-cured in a confined setting, the shrinkage they undergo generates stress at the bonded interface with the surrounding tooth structure. Often this stress is high enough to break the adhesive interface, causing a gap that leads to marginal staining, sensitivity and recurrent decay. This project will explore an alternative type of photo-initiator that can significantly reduce shrinkage stress. The new compound will be custom synthesized and its ability to initiate polymerization on a par with typical photo-initiator will be verified in a model composite using FTIR analysis. The polymerization stress of the model composite will be measured and compared with a composite containing typical photo-initiator. The in vitro wear resistance and fracture toughness of the composites containing novel initiator will be compared to composites containing typical initiator to ensure their clinical viability. Microleakage in class V restorations will be simulated in extracted human molars for the novel composites to demonstrate their superior marginal seal compared to a control composite. A composite that produces low polymerization stress would alleviate a long-standing problem in dentistry, with potential applications to other industries such as automobile and electronics manufacturing.