Maternal Drug Abuse Psychopathology and Child Adaptation

描述（由申请人提供）：本申请要求继续 提供资金，支持关于产妇药物滥用的作用的研究， 其他常见的精神疾病，与儿童的 调整结果。我们集团目前正在争取 关于适应不良、能力和脆弱性的全面数据， 8-17岁儿童及其母亲样本中的保护因素。我们 预计总基线样本约为350个儿童-母亲配对， 一半的母亲将被诊断为可卡因/阿片类药物依赖或滥用。 在拟议的项目中，我们试图重新评估这一队列约4 在初步评估后的几年里。 具体的目的是检查：（1）在何种程度上，产妇药物 滥用/依赖，而不是情感和焦虑的诊断， 常见的共病问题，与儿童的 随着时间的推移失调;（2）近端指标的程度 家庭功能紊乱与儿童死亡率增加有关。 随着时间的推移，精神病理学，以及终生母亲诊断的中介作用; (3)儿童、家庭一级保护力量的作用， （4）儿童精神病理学可能预示的程度 随着时间的推移，母亲的痛苦会增加。 基线研究需要测量不同的影响， 个人、家庭和社区各级，采用多种方法， 多信息源评估策略。根据以下方面评估儿童结局： 适应不良的诊断指标和维度指标，以及 日常能力。据我们所知，这将是第一批研究 为了获得这一广泛的前瞻性评估， 吸毒母亲的孩子，与一个匹配的对照样本。鉴于 发展时期包括一半的青年在青春期中期， 随访，一半接近成年-我们将能够检查因素 它既与严重调整的开始有关，也与严重调整的结晶有关。 滥用药物和品行障碍等问题。结果也 预计将对影响治疗和政策的信息量很大， 吸毒的母亲和他们的孩子，强调，例如， 需要关注这些母亲的心理和养育问题， 除了禁欲的问题，并反对神话，这些妇女是 不可避免地，对他们所照顾的未成年儿童来说， 生活在城市贫困中的母亲。

DESCRIPTION (provided by applicant): This application requests continuation of funding to support research on the role of maternal drug abuse, as opposed to other commonly co-occurring psychiatric disorders, in relation to children's adjustment outcomes. Our group is currently in the process of obtaining comprehensive data on maladjustment, competence, and vulnerability and protective factors in a sample of 8-17 year old children and their mothers. We anticipate a total baseline sample of about 350 child-mother dyads, and almost half of the mothers will have diagnoses of cocaine/opioid dependence or abuse. In the proposed project, we seek to re-assess this cohort approximately four years after the initial assessments. Specific aims are to examine: (1) the degree to which maternal drug abuse/dependence, as opposed to affective and anxiety diagnoses which are commonly comorbid problems, are linked with escalations in children's maladjustment over time; (2) the degree to which proximal indicators of disturbed family functioning are linked with increases in children's psychopathology over time, and mediate effects of lifetime maternal diagnoses; (3) the role of protective forces at the level of the child, the family, and the community; (4) the degree to which child psychopathology might presages increases in mothers' distress over time. The baseline study entailed measurement of diverse influences at the individual, family and community levels, with the use of a multi-method, multi-informant assessment strategy. Child outcomes were assessed in terms of both diagnostic and dimensional indicators of maladjustment, as well as aspects of everyday competence. To our knowledge, this will be among the first studies to obtain this breadth of prospective assessments on a large cohort of older children of addicted mothers, with a matched comparison sample. Given the developmental periods encompassed with half the youth in mid-adolescence at follow-up, and half approaching adulthood- we will be able to examine factors implicated both in the onset, and the crystallization, of serious adjustment problems such as substance abuse and conduct disturbances. Findings are also expected to be highly informative for treatments and policies affecting addicted mothers and their children, underscoring, for example, the critical need for attention to these mother's psychological and parenting problems in addition to issues of abstinence, and countering myths that these women are inevitably more inimical for minor children in their care than are any other highly stressed mothers, living in urban poverty.