Conference on Oxidative Mechanisms in Neurodegeneration

描述（由申请人提供）： 本申请寻求部分资助美国研究人员参加将于2003年8月9日至13日在中国桂林举行的题为“神经退行性疾病中的氧化机制”的研讨会。国际神经化学学会/亚太神经化学学会（ISN/APSN）将于8月2日至7日在香港举行。中枢神经系统（CNS）对氧化应激高度敏感，氧化应激改变许多代谢途径，导致细胞功能障碍。由于氧化应激的增加与许多与年龄相关的神经退行性疾病的病理生理学有关，包括阿尔茨海默病，帕金森病和中风，本次研讨会汇集了世界级的科学家，分享这些神经退行性疾病的氧化机制的新发现和见解。除了专注于与阿尔茨海默病，帕金森病，中风和受体信号通路相关的氧化机制的会议外，一个特别的会议将致力于讨论逆转和预防的新方法。因此，本次研讨会不仅为国际科学家和年轻的研究者提供了关注神经科学家非常感兴趣的重要主题的机制，也为中国以外的研究者提供了学习和与中国研究者在神经退行性疾病的基础和临床方面互动的机会。此外，正在制定计划，以便在一份国际公认的神经科学杂志上迅速发表专题讨论会的会议记录。

DESCRIPTION (provided by applicant): This application seeks funds for partial support of US investigators to attend a symposium entitled "Oxidative mechanisms in Neurodegenerative disorders" to be held in Guilin, China, August 9-13, 2003. The symposium is a satellite to the International Society of Neurochemistry/Asian Pacific Society of Neurochemistry (ISN/APSN) that will be held in Hong Kong, August 2-7. The Central Nervous System (CNS) is highly susceptible to oxidative stress, which alters many metabolic pathways leading to cellular dysfunction. Since increase in oxidative stress has been implicated in the pathophysiology of a number of age related neurodegenerative disorders, including AIzheimer's disease, Parkinson's disease and stroke, this symposium brings together world-class scientists to share new findings and insights on oxidative mechanisms underlying these neurodegenerative disorders. In addition to sessions focused on oxidative mechanisms associated with Alzheimer's disease, Parkinson disease, stroke, and receptor signaling pathways, a special session will be dedicated to discussing novel methods for invervention and prevention. Thus, this symposium not only provides mechanisms for international scientists and young investigators to focus on an import topic of immense interest to neuroscientists, it also provides opportunities for investigators outside of hina to learn and interact with Chinese investigators in basic and clinical aspects of neurodegenerative diseases. In addition, plans are in progress to provide rapid publication of the symposium proceedings in an internationally recognized neuroscience journal.