Assessment Of Ras And Renovascular Hypertension By Contr

本方案的目的是确定磁共振血管造影（MRA）和卡托普利磁共振肾造影（MRI）是否可以对肾血管性高血压危险患者提供全面的评估。尽管肾血管性高血压（肾动脉狭窄导致高血压）不常见，但它仍然是一种可纠正的高血压形式。目前评估肾血管性高血压患者的方法繁琐，包括多普勒超声、卡托普利肾造影、MRA和血管造影。本方案的目的是测试目前的金标准，卡托普利肾造影术和血管造影术与MRA和卡托普利MR肾造影术的组合。在这项研究中，高危患者接受了传统的卡托普利核医学重图，随后进行了磁共振重图和MRA。患者还呼吸一种富氧气体，称为碳，用于检测肾缺血。到目前为止，我们已经有6名志愿者和16名患者参与了该方案。我们预计在接下来的一年中，该方案的患者人数将继续增加。

The purpose of this protocol is to determine whether magnetic resonance angiography (MRA) and captopril magnetic resonance renography (MRI) can provide comprehensive evaluation of patients at risk for renovascular hypertension. Although renovascular hypertension (renal artery stenosis causing high blood pressure) is unusual, it nonetheless represents a correctable form of hypertension. The current methods of evaluating patients for renovascular hypertension are cumbersome and include Doppler sonography, captopril renography, MRA and angiography. The purpose of this protocol is to test the current gold standards, captopril renography and angiography against a combination of MRA and captopril MR renography. For this study, the at-risk patient undergoes a conventional captopril nuclear medicine renogram followed by an MR renogram and MRA. The patient also breathes an oxygen-rich-gas known as carbogen which is used to test for renal ischemia. To date, we have accrued 6 volunteers and 16 patients to this protocol. We anticipate continued patient accrual to this protocol over the coming year.